| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Beta-arrestin-1 |
|---|
| Ligand | BDBM50122872 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | >10000±n/a nM |
|---|
| Comments | PDSP_1544 |
|---|
| Citation |  Briejer, MR; Bosmans, JP; Van Daele, P; Jurzak, M; Heylen, L; Leysen, JE; Prins, NH; Schuurkes, JA The in vitro pharmacological profile of prucalopride, a novel enterokinetic compound. Eur J Pharmacol423:71-83 (2001) [PubMed] Article |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Beta-arrestin-1 |
|---|
| Name: | Beta-arrestin-1 |
|---|
| Synonyms: | ARRB1 | ARRB1_RABIT | Beta-arrestin-1 | Cholinergic, muscarinic | OPIATE Delta | PAF Platelet activating factor |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 46360.54 |
|---|
| Organism: | RABBIT |
|---|
| Description: | Cholinergic, muscarinic 0 RABBIT::Q95223 |
|---|
| Residue: | 410 |
|---|
| Sequence: | MGDKGTRVFKKASPNGKLTVYLGKRGFVDHIDLVDPVDGVVLVDPEYLKERRVYVTLTCA
FRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKKPLTRLQERLIKKLGEHAYPFTFEIP
PKLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLEEKIHKRNSVRLVIRKVQYAPERPGP
HPTAETTRLFLMSDKPLHLEASLDKEIYYHGEPIIVNVHVTNNTNKTVKKIKISVRQYAD
ICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLTPFLANNREKRGLALDGKLKHEDTNL
ASSTLMREGANREILGIIVSYKVKVKLVVSRGGDVAVELPFTLMHPKPKEEPPHREVPEN
ETPVDTNLIELDTNDDDIVFEDFARQRLKGMKDDKEEEDDVTGSPRLNDR
|
|
|
|---|
| BDBM50122872 |
|---|
| n/a |
|---|
| Name | BDBM50122872 |
|---|
| Synonyms: | 4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxylic acid [1-(3-methoxy-propyl)-piperidin-4-yl]-amide | CHEMBL117287 | PRUCALOPRIDE | US9663465, prucalopride |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H26ClN3O3 |
|---|
| Mol. Mass. | 367.87 |
|---|
| SMILES | COCCCN1CCC(CC1)NC(=O)c1cc(Cl)c(N)c2CCOc12 |
|---|
| Structure | 
|
|---|
Search and Browse
