| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1B |
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| Ligand | BDBM85826 |
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| Substrate/Competitor | n/a |
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| Ki | 1400±n/a nM |
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| Comments | PDSP_2299 |
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| Citation |  Rënyi, L; Evenden, JL; Fowler, CJ; Jerning, E; Kelder, D; Lake-Bakaar, D; Larsson, LG; Mohell, N; Sällemark, M; Ross, SB The pharmacological profile of (R)-3,4-dihydro-N-isopropyl-3-(N-isopropyl-N-propylamino)-2H-1-benzopyran-5-carboxamide, a selective 5-hydroxytryptamine(1A) receptor agonist. J Pharmacol Exp Ther299:883-93 (2001) [PubMed] |
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| More Info.: | Get all data from this article |
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| 5-hydroxytryptamine receptor 1B |
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| Name: | 5-hydroxytryptamine receptor 1B |
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| Synonyms: | 5-HT1B | 5-hydroxytryptamine serotonin receptor 1B | HTR1B |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 43142.15 |
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| Organism: | BOVINE |
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| Description: | L8IGV0 |
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| Residue: | 389 |
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| Sequence: | MEAVAAQCPQPPSASSQTGLSQANLSAGPSHNCSAAEEYIYQDFIALPWKVVVVLLLALF
TLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQ
VVCDLWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSIC
ISLPPFFWRQAKAEAMSNCVVNTDHVLYTVYSTVGAFYFPTLLLIALYGRIYVEARSRIL
KQTPNRTGKRLTRAQLITDSPGSTSSVTSINSRAPEVPSESGSPVYVNQVKVRVSDALLE
KKKLMAARERKATKTLGIILGAFIVCWLPFFIISLAIPICTSCWFHQAIFDFFTWLGYLN
SLINPIIYTMSNEDFKQAFHKLIGFKCTN
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| BDBM85826 |
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| n/a |
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| Name | BDBM85826 |
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| Synonyms: | (R)-N-Isopropyl-3-[isopropyl(propyl)amino]-3,4-dihydro-2H-1-benzopyran-5-carboxamide | NAE-086 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H30N2O2 |
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| Mol. Mass. | 318.4537 |
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| SMILES | CCCN(C(C)C)[C@H]1COc2cccc(C(=O)NC(C)C)c2C1 |
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| Structure | 
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