| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 6 |
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| Ligand | BDBM85827 |
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| Substrate/Competitor | n/a |
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| Ki | >10000±n/a nM |
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| Comments | PDSP_2298 |
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| Citation |  Rënyi, L; Evenden, JL; Fowler, CJ; Jerning, E; Kelder, D; Lake-Bakaar, D; Larsson, LG; Mohell, N; Sällemark, M; Ross, SB The pharmacological profile of (R)-3,4-dihydro-N-isopropyl-3-(N-isopropyl-N-propylamino)-2H-1-benzopyran-5-carboxamide, a selective 5-hydroxytryptamine(1A) receptor agonist. J Pharmacol Exp Ther299:883-93 (2001) [PubMed] |
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| More Info.: | Get all data from this article |
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| 5-hydroxytryptamine receptor 6 |
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| Name: | 5-hydroxytryptamine receptor 6 |
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| Synonyms: | 5-HT-6 | 5-HT6 | 5-hydroxytryptamine receptor 6 | 5HT6R_RAT | Htr6 | ST-B17 | Serotonin (5-HT) receptor | Serotonin 6 (5-HT6) receptor | Serotonin receptor 6 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 46945.51 |
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| Organism: | RAT |
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| Description: | 5-HT6 HTR6 RAT::P31388 |
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| Residue: | 436 |
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| Sequence: | MVPEPGPVNSSTPAWGPGPPPAPGGSGWVAAALCVVIVLTAAANSLLIVLICTQPALRNT
SNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLI
SLDRYLLILSPLRYKLRMTAPRALALILGAWSLAALASFLPLLLGWHELGKARTPAPGQC
RLLASLPFVLVASGVTFFLPSGAICFTYCRILLAARKQAVQVASLTTGTAGQALETLQVP
RTPRPGMESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIAQAVCDCISPG
LFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCVHCPPEHRPALPPPPCGPLTAVP
DQASACSRCCLCLCRQTQIQTPLQGAPRACSSQPSFCCLERPPGTPRHPPGPPLWSTSLS
QTLWSLRYGRIHSVPP
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| BDBM85827 |
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| n/a |
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| Name | BDBM85827 |
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| Synonyms: | (R)-3-[Isopropyl(propyl)amino]-3,4-dihydro-2H-1-benzopyran-5-carboxamide | NAE-111 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H24N2O2 |
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| Mol. Mass. | 276.374 |
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| SMILES | CCCN(C(C)C)[C@H]1COc2cccc(C(N)=O)c2C1 |
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| Structure | 
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