| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 4 |
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| Ligand | BDBM86038 |
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| Substrate/Competitor | n/a |
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| Ki | 0.6±n/a nM |
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| Comments | PDSP_2965 |
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| Citation |  Moser, PC; Bergis, OE; Jegham, S; Lochead, A; Duconseille, E; Terranova, JP; Caille, D; Berque-Bestel, I; Lezoualc'h, F; Fischmeister, R; Dumuis, A; Bockaert, J; George, P; Soubrié, P; Scatton, B SL65.0155, a novel 5-hydroxytryptamine(4) receptor partial agonist with potent cognition-enhancing properties. J Pharmacol Exp Ther302:731-41 (2002) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| 5-hydroxytryptamine receptor 4 |
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| Name: | 5-hydroxytryptamine receptor 4 |
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| Synonyms: | 5-HT-4 | 5-HT4 | 5-HT4S | 5-HT4a | 5-HT4b | 5-HT4c | 5-HT4d | 5-HT4hb | 5-hydroxytryptamine receptor 4 | 5-hydroxytryptamine receptor 4 (5-HT4) | 5HT4R_HUMAN | HTR4 | Serotonin (5-HT) receptor | Serotonin (5-HT3) receptor | Serotonin 4 (5-HT4) receptor | Serotonin Receptor 4 |
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| Type: | Enzyme |
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| Mol. Mass.: | 43767.54 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q13639 |
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| Residue: | 388 |
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| Sequence: | MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV
SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY
AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN
STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP
QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL
GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLRD
AVECGGQWESQCHPPATSPLVAAQPSDT
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| BDBM86038 |
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| n/a |
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| Name | BDBM86038 |
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| Synonyms: | SL65.0155 | SL650155 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H25ClN4O4 |
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| Mol. Mass. | 456.922 |
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| SMILES | Nc1c(Cl)cc(-c2nn(C3CCN(CCc4ccccc4)CC3)c(=O)o2)c2OCCOc12 |
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| Structure | 
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