| Reaction Details |
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 | Report a problem with these data |
| Target | Casein kinase I isoform delta |
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| Ligand | BDBM25116 |
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| Substrate/Competitor | n/a |
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| Ki | 1060±n/a nM |
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| Comments | PDSP_6409 |
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| Citation |  Bain, J; McLauchlan, H; Elliott, M; Cohen, P The specificities of protein kinase inhibitors: an update. Biochem J371:199-204 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Casein kinase I isoform delta |
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| Name: | Casein kinase I isoform delta |
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| Synonyms: | CK1, delta | Casein kinase 1 Delta | Casein kinase I delta | Casein kinase I isoform delta | Csnk1d | Hckid | KC1D_RAT | casein kinase 1, delta |
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| Type: | Enzyme |
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| Mol. Mass.: | 47342.73 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | Q06486 |
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| Residue: | 415 |
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| Sequence: | MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQ
GGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH
SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA
SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL
CKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRA
ADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHTANTSPRPV
SGMERERKVSMRLHRGAPVNVSSSDLTGRQDTSRMSTSQIPGRVASSGLQSVVHR
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| BDBM25116 |
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| n/a |
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| Name | BDBM25116 |
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| Synonyms: | 1-tert-butyl-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | CHEMBL306380 | PP1 | US10688093, Compound PP1 (Pfizer) | US10807986, Comparative compound 1 | US11046696, Compound 1 of Comparative Examples | US11701353, PP1 (Pfizer) | cid_1400 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H19N5 |
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| Mol. Mass. | 281.3556 |
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| SMILES | Cc1ccc(cc1)-c1nn(c2ncnc(N)c12)C(C)(C)C |
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| Structure | 
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