| Reaction Details |
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 | Report a problem with these data |
| Target | Cyclin-dependent kinase 2 |
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| Ligand | BDBM7393 |
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| Substrate/Competitor | n/a |
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| Ki | 590±n/a nM |
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| Comments | PDSP_6406 |
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| Citation |  Bain, J; McLauchlan, H; Elliott, M; Cohen, P The specificities of protein kinase inhibitors: an update. Biochem J371:199-204 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Cyclin-dependent kinase 2 |
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| Name: | Cyclin-dependent kinase 2 |
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| Synonyms: | CDK2 | CDK2-Kinase | CDK2_HUMAN | CDKN2 | Cell division protein kinase 2 | Cyclin-dependent kinase 2 (CDK2) | Protein cereblon/Cyclin-dependent kinase 2 | p33 protein kinase |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 33938.17 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P24941 |
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| Residue: | 298 |
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| Sequence: | MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH
PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS
HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY
STAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSF
PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
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| BDBM7393 |
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| n/a |
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| Name | BDBM7393 |
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| Synonyms: | 3-[(2Z,3E)-3-(hydroxyimino)-2,3-dihydro-1H-indol-2-ylidene]-2,3-dihydro-1H-indol-2-one | CHEMBL397695 | Indirubin-3 -monoxime | Indirubin-3-monoxime | Indirubin-3monoxime | indirubin deriv. 7h |
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| Type | n/a |
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| Emp. Form. | C16H11N3O2 |
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| Mol. Mass. | 277.2774 |
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| SMILES | O=Nc1c([nH]c2ccccc12)C1C(=O)Nc2ccccc12 |
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| Structure | 
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