| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(1A) dopamine receptor |
|---|
| Ligand | BDBM86177 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 140±n/a nM |
|---|
| Comments | PDSP_4966 |
|---|
| Citation |  Qandil, AM; Lewis, MM; Jassen, A; Leonard, SK; Mailman, RB; Nichols, DE Synthesis and pharmacological evaluation of substituted naphth[1,2,3-de]isoquinolines (dinapsoline analogues) as D1 and D2 dopamine receptor ligands. Bioorg Med Chem11:1451-64 (2003) [PubMed] Article |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| D(1A) dopamine receptor |
|---|
| Name: | D(1A) dopamine receptor |
|---|
| Synonyms: | DOPAMINE D1 | DRD1_RAT | Dopamine D1 high | Dopamine D1 low | Dopamine receptor | Dopamine receptor D1 | Dopamine1-like | Drd1 | Drd1a |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 49429.75 |
|---|
| Organism: | RAT |
|---|
| Description: | P18901 |
|---|
| Residue: | 446 |
|---|
| Sequence: | MAPNTSTMDEAGLPAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNF
FVISLAVSDLLVAVLVMPWKAVAEIAGFWPLGPFCNIWVAFDIMCSTASILNLCVISVDR
YWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFTSLED
TEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKN
CQTTAGNGNPVECAQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCGS
EETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFQKAFSTLLGCYRLCPTTNNAIET
VSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIAKPLEKLSPAL
SVILDYDTDVSLEKIQPVTHSGQHST
|
|
|
|---|
| BDBM86177 |
|---|
| n/a |
|---|
| Name | BDBM86177 |
|---|
| Synonyms: | Dinapsoline,(+/-)-4-Methyl-N-allyl |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H21NO2 |
|---|
| Mol. Mass. | 307.3862 |
|---|
| SMILES | Cc1ccc2Cc3c(O)c(O)ccc3[C@@H]3CN(CC=C)Cc1c23 |
|---|
| Structure | 
|
|---|
Search and Browse
