| Reaction Details |
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 | Report a problem with these data |
| Target | D(1A) dopamine receptor |
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| Ligand | BDBM50274531 |
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| Substrate/Competitor | n/a |
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| Ki | 1.18±n/a nM |
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| Comments | PDSP_4926 |
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| Citation |  Neumeyer, JL; Kula, NS; Bergman, J; Baldessarini, RJ Receptor affinities of dopamine D1 receptor-selective novel phenylbenzazepines. Eur J Pharmacol474:137-40 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| D(1A) dopamine receptor |
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| Name: | D(1A) dopamine receptor |
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| Synonyms: | DOPAMINE D1 | DRD1_RAT | Dopamine D1 high | Dopamine D1 low | Dopamine receptor | Dopamine receptor D1 | Dopamine1-like | Drd1 | Drd1a |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 49429.75 |
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| Organism: | RAT |
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| Description: | P18901 |
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| Residue: | 446 |
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| Sequence: | MAPNTSTMDEAGLPAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNF
FVISLAVSDLLVAVLVMPWKAVAEIAGFWPLGPFCNIWVAFDIMCSTASILNLCVISVDR
YWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFTSLED
TEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKN
CQTTAGNGNPVECAQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCGS
EETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFQKAFSTLLGCYRLCPTTNNAIET
VSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIAKPLEKLSPAL
SVILDYDTDVSLEKIQPVTHSGQHST
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| BDBM50274531 |
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| n/a |
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| Name | BDBM50274531 |
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| Synonyms: | 6-Chloro-3-methyl-1-m-tolyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol; hydrobromide | 6-chloro-3-methyl-1-m-tolyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol hydrobromide | CHEMBL520992 | CHEMBL574558 | SKF-83959 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H20ClNO2 |
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| Mol. Mass. | 317.81 |
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| SMILES | CN1CCc2c(Cl)c(O)c(O)cc2C(C1)c1cccc(C)c1 |
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| Structure | 
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