| Reaction Details |
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 | Report a problem with these data |
| Target | Gamma-aminobutyric acid type B receptor subunit 1 |
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| Ligand | BDBM86283 |
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| Substrate/Competitor | n/a |
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| Ki | 32.36±n/a nM |
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| Comments | PDSP_3384 |
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| Citation |  Urwyler, S; Pozza, MF; Lingenhoehl, K; Mosbacher, J; Lampert, C; Froestl, W; Koller, M; Kaupmann, K N,N'-Dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine (GS39783) and structurally related compounds: novel allosteric enhancers of gamma-aminobutyric acidB receptor function. J Pharmacol Exp Ther307:322-30 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Gamma-aminobutyric acid type B receptor subunit 1 |
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| Name: | Gamma-aminobutyric acid type B receptor subunit 1 |
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| Synonyms: | GABA B | GABA B receptor | GABA uptake | GABA-B receptor 1 | GABA-B-R1 | GABA-BR1 | GABABR1 | GABR1_RAT | Gabbr1 | Gb1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 111548.69 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | Q9Z0U4 |
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| Residue: | 991 |
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| Sequence: | MLLLLLVPLFLRPLGAGGAQTPNATSEGCQIIHPPWEGGIRYRGLTRDQVKAINFLPVDY
EIEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLPA
LDGARVEFRCDPDFHLVGSSRSVCSQGQWSTPKPHCQVNRTPHSERRAVYIGALFPMSGG
WPGGQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYELLYNDPIKII
LMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVKLF
EKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPVKNLKRQDARI
IVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKTYDPSINCTVEEMTEAVEG
HITTEIVMLNPANTRSISNMTSQEFVEKLTKRLKRHPEETGGFQEAPLAYDAIWALALAL
NKTSGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVSGHVVFDASGSRMAWTLIEQ
LQGGSYKKIGYYDSTKDDLSWSKTDKWIGGSPPADQTLVIKTFRFLSQKLFISVSVLSSL
GIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGRSQFPF
VCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLLVGMD
VLTLAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEHCSSKKMNTWLGELWSFAVSSD
VQRRATVGGDSPICVWPAPESIFYGYKGLLLLLGIFLAYETKSVSTEKINDHRAVGMAIY
NVAVLCLITAPVTMILSSQQDAAFAFASLAIVFSSYITLVVLFVPKMRRLITRGEWQSET
QDTMKTGSSTNNNEEEKSRLLEKENRELEKIIAEKEERVSELRHQLQSRQQLRSRRHPPT
PPDPSGGLPRGPSEPPDRLSCDGSRVHLLYK
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| BDBM86283 |
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| n/a |
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| Name | BDBM86283 |
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| Synonyms: | CAS_345-78-8 | CAS_39069-52-8 | GS 39783 | N,N'-Dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine | NSC_5032 | Pseudoephedrine,(+) |
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| Type | Small organic molecule |
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| Emp. Form. | C15H23N5O2S |
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| Mol. Mass. | 337.44 |
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| SMILES | CSc1nc(NC2CCCC2)c(c(NC2CCCC2)n1)[N+]([O-])=O |
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| Structure | 
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