| Reaction Details |
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 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M1 |
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| Ligand | BDBM86290 |
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| Substrate/Competitor | n/a |
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| Ki | 91.20±n/a nM |
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| Comments | PDSP_3133 |
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| Citation |  De Amici, M; Conti, P; Fasoli, E; Barocelli, E; Ballabeni, V; Bertoni, S; Impicciatore, M; Roth, BL; Ernsberger, P; De Micheli, C Synthesis and in vitro pharmacology of novel heterocyclic muscarinic ligands. Farmaco58:739-48 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Muscarinic acetylcholine receptor M1 |
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| Name: | Muscarinic acetylcholine receptor M1 |
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| Synonyms: | ACM1_HUMAN | CHRM1 | Cholinergic receptor, muscarinic 1 | Cholinergic, muscarinic M1 |
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| Type: | Protein |
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| Mol. Mass.: | 51442.54 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P11229 |
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| Residue: | 460 |
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| Sequence: | MNTSAPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVN
NYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLIS
FDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYI
QFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSS
SERSQPGAEGSPETPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEV
VIKMPMVDPEAQAPTKQPPRSSPNTVKRPTKKGRDRAGKGQKPRGKEQLAKRKTFSLVKE
KKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTINPMCYAL
CNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
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| BDBM86290 |
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| n/a |
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| Name | BDBM86290 |
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| Synonyms: | 3-[4-(2-Methyl-1H-imidazol-1-yl)-2-butynyl]oxy-delta2-isoxazoline sesquifumarate |
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| Type | Small organic molecule |
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| Emp. Form. | C11H13N3O2 |
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| Mol. Mass. | 219.2398 |
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| SMILES | Cc1nccn1CC#CCOC1=NOCC1 |t:12| |
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| Structure | 
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