| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M1 |
|---|
| Ligand | BDBM86293 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 870.96±n/a nM |
|---|
| Comments | PDSP_3136 |
|---|
| Citation |  De Amici, M; Conti, P; Fasoli, E; Barocelli, E; Ballabeni, V; Bertoni, S; Impicciatore, M; Roth, BL; Ernsberger, P; De Micheli, C Synthesis and in vitro pharmacology of novel heterocyclic muscarinic ligands. Farmaco58:739-48 (2003) [PubMed] Article |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Muscarinic acetylcholine receptor M1 |
|---|
| Name: | Muscarinic acetylcholine receptor M1 |
|---|
| Synonyms: | ACM1_HUMAN | CHRM1 | Cholinergic receptor, muscarinic 1 | Cholinergic, muscarinic M1 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 51442.54 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P11229 |
|---|
| Residue: | 460 |
|---|
| Sequence: | MNTSAPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVN
NYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLIS
FDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYI
QFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSS
SERSQPGAEGSPETPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEV
VIKMPMVDPEAQAPTKQPPRSSPNTVKRPTKKGRDRAGKGQKPRGKEQLAKRKTFSLVKE
KKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTINPMCYAL
CNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
|
|
|
|---|
| BDBM86293 |
|---|
| n/a |
|---|
| Name | BDBM86293 |
|---|
| Synonyms: | 3-[4-(2-Methyl-3-(4-bromobenzyl)-1H-imidazolium-1-yl)-2-butynyl]oxyisoxazole bromide | CAS_0 | NSC_0 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H15BrN3O2 |
|---|
| Mol. Mass. | 373.223 |
|---|
| SMILES | Cc1n(CC#CCOc2ccon2)cc[n+]1-c1ccc(Br)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
