| Reaction Details |
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 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M3 |
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| Ligand | BDBM86294 |
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| Substrate/Competitor | n/a |
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| Ki | 6.31±n/a nM |
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| Comments | PDSP_3134 |
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| Citation |  De Amici, M; Conti, P; Fasoli, E; Barocelli, E; Ballabeni, V; Bertoni, S; Impicciatore, M; Roth, BL; Ernsberger, P; De Micheli, C Synthesis and in vitro pharmacology of novel heterocyclic muscarinic ligands. Farmaco58:739-48 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Muscarinic acetylcholine receptor M3 |
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| Name: | Muscarinic acetylcholine receptor M3 |
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| Synonyms: | ACM3_HUMAN | CHRM3 | Cholinergic, muscarinic M3 | Muscarinic Receptors M3 | Muscarinic receptor M3 | RecName: Full=Muscarinic acetylcholine receptor M3 |
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| Type: | Enzyme |
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| Mol. Mass.: | 66151.03 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P20309 |
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| Residue: | 590 |
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| Sequence: | MTLHNNSTTSPLFPNISSSWIHSPSDAGLPPGTVTHFGSYNVSRAAGNFSSPDGTTDDPL
GGHTVWQVVFIAFLTGILALVTIIGNILVIVSFKVNKQLKTVNNYFLLSLACADLIIGVI
SMNLFTTYIIMNRWALGNLACDLWLAIDYVASNASVMNLLVISFDRYFSITRPLTYRAKR
TTKRAGVMIGLAWVISFVLWAPAILFWQYFVGKRTVPPGECFIQFLSEPTITFGTAIAAF
YMPVTIMTILYWRIYKETEKRTKELAGLQASGTEAETENFVHPTGSSRSCSSYELQQQSM
KRSNRRKYGRCHFWFTTKSWKPSSEQMDQDHSSSDSWNNNDAAASLENSASSDEEDIGSE
TRAIYSIVLKLPGHSTILNSTKLPSSDNLQVPEEELGMVDLERKADKLQAQKSVDDGGSF
PKSFSKLPIQLESAVDTAKTSDVNSSVGKSTATLPLSFKEATLAKRFALKTRSQITKRKR
MSLVKEKKAAQTLSAILLAFIITWTPYNIMVLVNTFCDSCIPKTFWNLGYWLCYINSTVN
PVCYALCNKTFRTTFKMLLLCQCDKKKRRKQQYQQRQSVIFHKRAPEQAL
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| BDBM86294 |
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| n/a |
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| Name | BDBM86294 |
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| Synonyms: | 3-[4-(2,3-Dimethyl-1H-imidazolium-1-yl)-2-butynyl]oxy-delta2-isoxazoline iodide | CAS_0 | NSC_0 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H16N3O2 |
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| Mol. Mass. | 234.2738 |
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| SMILES | Cc1n(CC#CCOC2=NOCC2)cc[n+]1C |t:8| |
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| Structure | 
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