| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Neuronal acetylcholine receptor subunit alpha-3 |
|---|
| Ligand | BDBM50047021 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 480±n/a nM |
|---|
| Comments | PDSP_1085 |
|---|
| Citation |  Jensen, AA; Mikkelsen, I; Frølund, B; Bräuner-Osborne, H; Falch, E; Krogsgaard-Larsen, P Carbamoylcholine homologs: novel and potent agonists at neuronal nicotinic acetylcholine receptors. Mol Pharmacol64:865-75 (2003) [PubMed] Article |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Neuronal acetylcholine receptor subunit alpha-3 |
|---|
| Name: | Neuronal acetylcholine receptor subunit alpha-3 |
|---|
| Synonyms: | ACHA3_RAT | Acra3 | Chrna3 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 56995.52 |
|---|
| Organism: | Rattus norvegicus (Rat) |
|---|
| Description: | P04757 |
|---|
| Residue: | 499 |
|---|
| Sequence: | MGVVLLPPPLSMLMLVLMLLPAASASEAEHRLFQYLFEDYNEIIRPVANVSHPVIIQFEV
SMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWKPSDYQGVEFMRVPAEKIWKPDIVLYNN
ADGDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAK
IDLVLIGSSMNLKDYWESGEWAIIKAPGYKHEIKYNCCEEIYQDITYSLYIRRLPLFYTI
NLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGE
YLLFTMIFVTLSIVITVFVLNVHYRTPTTHTMPTWVKAVFLNLLPRVMFMTRPTSGEGDT
PKTRTFYGAELSNLNCFSRADSKSCKEGYPCQDGTCGYCHHRRVKISNFSANLTRSSSSE
SVNAVLSLSALSPEIKEAIQSVKYIAENMKAQNVAKEIQDDWKYVAMVIDRIFLWVFILV
CILGTAGLFLQPLMARDDT
|
|
|
|---|
| BDBM50047021 |
|---|
| n/a |
|---|
| Name | BDBM50047021 |
|---|
| Synonyms: | 2-(6-(2-hydroxy-2-phenylethyl)-1-methylpiperidin-2-yl)-1-phenylethanone | 2-[6-(2-Hydroxy-2-phenyl-ethyl)-1-methyl-piperidin-2-yl]-1-phenyl-ethanone | 2-[6-(2-Hydroxy-2-phenyl-ethyl)-1-methyl-piperidin-2-yl]-1-phenyl-ethanone (lobeline) | CHEMBL15476 | Lobeline | Lobeline, (-) | Lobeline,Alpha |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H27NO2 |
|---|
| Mol. Mass. | 337.4553 |
|---|
| SMILES | CN1C(CC(O)c2ccccc2)CCCC1CC(=O)c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
