| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Neuronal acetylcholine receptor subunit alpha-4 |
|---|
| Ligand | BDBM50026220 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 7000±n/a nM |
|---|
| Comments | PDSP_3246 |
|---|
| Citation |  Eaton, JB; Peng, JH; Schroeder, KM; George, AA; Fryer, JD; Krishnan, C; Buhlman, L; Kuo, YP; Steinlein, O; Lukas, RJ Characterization of human alpha 4 beta 2-nicotinic acetylcholine receptors stably and heterologously expressed in native nicotinic receptor-null SH-EP1 human epithelial cells. Mol Pharmacol64:1283-94 (2003) [PubMed] Article |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Neuronal acetylcholine receptor subunit alpha-4 |
|---|
| Name: | Neuronal acetylcholine receptor subunit alpha-4 |
|---|
| Synonyms: | ACHA4_HUMAN | CHRNA4 | CHRNA4 protein | NACRA4 | Neuronal acetylcholine receptor protein alpha-4 subunit | Neuronal acetylcholine receptor subunit alpha 4 beta 2 | Nicotinic acetylcholine receptor alpha4/beta2/alpha5 |
|---|
| Type: | n/a |
|---|
| Mol. Mass.: | 69963.49 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | NACHRA4 |
|---|
| Residue: | 627 |
|---|
| Sequence: | MELGGPGAPRLLPPLLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISD
VVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWR
PDIVLYNNADGDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFG
SWTYDKAKIDLVNMHSRVDQLDFWESGEWVIVDAVGTYNTRKYECCAEIYPDITYAFVIR
RLPLFYTINLIIPCLLISCLTVLVFYLPSECGEKITLCISVLLSLTVFLLLITEIIPSTS
LVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPRTHTMPTWVRRVFLDIVPRLLLMKR
PSVVKDNCRRLIESMHKMASAPRFWPEPEGEPPATSGTQSLHPPSPSFCVPLDVPAEPGP
SCKSPSDQLPPQQPLEAEKASPHPSPGPCRPPHGTQAPGLAKARSLSVQHMSSPGEAVEG
GVRCRSRSIQYCVPRDDAAPEADGQAAGALASRNTHSAELPPPDQPSPCKCTCKKEPSSV
SPSATVKTRSTKAPPPHLPLSPALTRAVEGVQYIADHLKAEDTDFSVKEDWKYVAMVIDR
IFLWMFIIVCLLGTVGLFLPPWLAGMI
|
|
|
|---|
| BDBM50026220 |
|---|
| n/a |
|---|
| Name | BDBM50026220 |
|---|
| Synonyms: | 2-hydroxy-N,N,N-trimethylethanaminium | CHEMBL282468 | CHEMBL293410 | CHEMBL920 | N-trimethylethanolamine | OXTRIPHYLLINE | choline | trimethylethanolamine |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C5H14NO |
|---|
| Mol. Mass. | 104.1702 |
|---|
| SMILES | C[N+](C)(C)CCO |
|---|
| Structure | 
|
|---|
Search and Browse
