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Target5-hydroxytryptamine receptor 1B
LigandBDBM86441
Substrate/Competitorn/a
Ki 1000±n/a nM
CommentsPDSP_3924
Citation Kimura, YHatanaka, KNaitou, YMaeno, KShimada, IKoakutsu, AWanibuchi, FYamaguchi, T Pharmacological profile of YM348, a novel, potent and orally active 5-HT2C receptor agonist. Eur J Pharmacol483:37-43 (2004) [PubMed]  Article
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5-hydroxytryptamine receptor 1B
Name:5-hydroxytryptamine receptor 1B
Synonyms:5-HT1B | 5HT1B_CANLF | HTR1B
Type:Enzyme Catalytic Domain
Mol. Mass.:42942.98
Organism:Canis lupus familiaris (Dog) (Canis familiaris)
Description:5-HT1B HTR1B 0::P79250
Residue:389
Sequence:
MEAAGAPCAPPPPAGSQTGAPPANLSSAPHNCSAEGYIYQDSVALPWKVLLVILLALITL
ATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVV
CDLWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISIS
LPPFFWRQAKAEEEVSDCVVNTDHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRILK
QTPNRTGKRLTRAQLITDSPGSTSSVTSVNSRAPDVPSESGSPVYVNQVKVRVSDALLEK
KKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHLAIFDFFTWLGYLN
SLINPIIYTMSNEDFKQAFHKLIRFKCAG
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BDBM86441
n/a
NameBDBM86441
Synonyms:CAS_3045225 | NSC_3045225 | YM348
TypeSmall organic molecule
Emp. Form.C14H17N3O
Mol. Mass.243.3043
SMILESCCc1cc2c(ccc3cnn(CC(C)N)c23)o1
Structure
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