| Reaction Details |
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 | Report a problem with these data |
| Target | P2X purinoceptor 2 |
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| Ligand | BDBM86486 |
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| Substrate/Competitor | n/a |
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| Ki | 14.5±n/a nM |
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| Comments | PDSP_4074 |
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| Citation |  Jarvis, MF; Bianchi, B; Uchic, JT; Cartmell, J; Lee, CH; Williams, M; Faltynek, C [3H]A-317491, a novel high-affinity non-nucleotide antagonist that specifically labels human P2X2/3 and P2X3 receptors. J Pharmacol Exp Ther310:407-16 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| P2X purinoceptor 2 |
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| Name: | P2X purinoceptor 2 |
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| Synonyms: | ATP receptor | P2RX2 | P2RX2_HUMAN | P2X2 | Purinergic receptor | PurinergicP2X2/3 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 51765.18 |
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| Organism: | Homo sapiens (Human) |
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| Description: | PurinergicP2X2/3 0 HUMAN::Q9UBL9 |
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| Residue: | 471 |
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| Sequence: | MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYV
FIVQKSYQESETGPESSIITKVKGITTSEHKVWDVEEYVKPPEGGSVFSIITRVEATHSQ
TQGTCPESIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVED
GASVSQFLGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFK
LGFIVEKAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYN
FRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCD
WILLTFMNKNKVYSHKKFDKVCTPSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSG
QEGQQGAECGPAFPPLRPCPISAPSEQMVDTPASEPAQASTPTDPKGLAQL
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| BDBM86486 |
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| n/a |
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| Name | BDBM86486 |
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| Synonyms: | ATP,TNP | CAS_644357 | NSC_644357 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H12N8O19P3 |
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| Mol. Mass. | 713.2327 |
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| SMILES | [#7]-c1ncnc2n(cnc12)-[#6]-1-[#8]-[#6](-[#6]-[#8]P([#8-])(=O)[#8]P([#8-])(=O)[#8]P([#8-])([#8-])=O)-[#6]-2-[#8]C3([#8]-[#6]-1-2)[#6](=[#6]\[#6](-[#6]=[#6]3-[#7+](-[#8-])=O)=[#7+](/[#8-])-[#8-])-[#7+](-[#8-])=O |c:36,39| |
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| Structure | 
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