| Reaction Details |
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 | Report a problem with these data |
| Target | Neuromedin-B receptor |
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| Ligand | BDBM86498 |
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| Substrate/Competitor | n/a |
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| Ki | 831±n/a nM |
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| Comments | PDSP_3742 |
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| Citation |  Mantey, SA; Coy, DH; Entsuah, LK; Jensen, RT Development of bombesin analogs with conformationally restricted amino acid substitutions with enhanced selectivity for the orphan receptor human bombesin receptor subtype 3. J Pharmacol Exp Ther310:1161-70 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Neuromedin-B receptor |
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| Name: | Neuromedin-B receptor |
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| Synonyms: | Bombesin 1 | NMB-R | NMBR | NMBR_HUMAN | Neuromedin B | Neuromedin B receptor | Neuromedin-B receptor | Neuromedin-B-preferring bombesin receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 43447.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Bombesin 1 NMBR 0::P28336 |
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| Residue: | 390 |
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| Sequence: | MPSKSLSNLSVTTGANESGSVPEGWERDFLPASDGTTTELVIRCVIPSLYLLIITVGLLG
NIMLVKIFITNSAMRSVPNIFISNLAAGDLLLLLTCVPVDASRYFFDEWMFGKVGCKLIP
VIQLTSVGVSVFTLTALSADRYRAIVNPMDMQTSGALLRTCVKAMGIWVVSVLLAVPEAV
FSEVARISSLDNSSFTACIPYPQTDELHPKIHSVLIFLVYFLIPLAIISIYYYHIAKTLI
KSAHNLPGEYNEHTKKQMETRKRLAKIVLVFVGCFIFCWFPNHILYMYRSFNYNEIDPSL
GHMIVTLVARVLSFGNSCVNPFALYLLSESFRRHFNSQLCCGRKSYQERGTSYLLSSSAV
RMTSLKSNAKNMVTNSVLLNGHSMKQEMAL
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| BDBM86498 |
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| n/a |
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| Name | BDBM86498 |
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| Synonyms: | CAS_0 | NSC_0 | [D-Tyr6,(S)-Apa11-3Cl,Phe13,Nle14]Bn(6-14) |
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| Type | Small organic molecule |
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| Emp. Form. | C63H79ClN14O11 |
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| Mol. Mass. | 1243.842 |
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| SMILES | CCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)C[C@@H](NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](N)Cc1ccc(O)cc1)C(C)C)c1cccc(Cl)c1)C(N)=O |r| |
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| Structure | 
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