| Reaction Details |
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 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
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| Ligand | BDBM86518 |
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| Substrate/Competitor | n/a |
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| Ki | 183±n/a nM |
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| Comments | PDSP_669 |
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| Citation |  Gilbert, AK; Hosztafi, S; Mahurter, L; Pasternak, GW Pharmacological characterization of dihydromorphine, 6-acetyldihydromorphine and dihydroheroin analgesia and their differentiation from morphine. Eur J Pharmacol492:123-30 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Kappa-type opioid receptor |
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| Name: | Kappa-type opioid receptor |
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| Synonyms: | Kappa Opioid Receptor | OPIATE Kappa | OPRK1 | OPRK_CAVPO | Opiate Kappa 1 | mu/kappa opioid receptor |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 42744.99 |
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| Organism: | Cavia porcellus (domestic guinea pig) |
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| Description: | P41144 |
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| Residue: | 380 |
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| Sequence: | MGRRRQGPAQPASELPARNACLLPNGSAWLPGWAEPDGNGSAGPQDEQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIILGGTKVREDVDIIECSLQFPDDDYSWWDLFMKICVFVFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFIICWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPIKMRMERQSTSRV
RNTVQDPAYMRNVDGVNKPV
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| BDBM86518 |
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| n/a |
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| Name | BDBM86518 |
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| Synonyms: | CAS_509-60-4 | DIHYDROMORPHINE | NSC_273032 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H21NO3 |
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| Mol. Mass. | 287.3535 |
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| SMILES | CN1CCC23C4Oc5c2c(CC1C3CCC4O)ccc5O |TLB:13:12:1.2.3:10.9.8| |
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| Structure | 
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