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TargetCholinergic, Nicotinic Alpha6Beta3Beta4Alpha5
LigandBDBM86241
Substrate/Competitorn/a
Ki>10000±n/a nM
CommentsPDSP_666
Citation Grinevich VPLetchworth SRLindenberger KAMenager JMary VSadieva KABuhlman LMBohme GAPradier LBenavides JLukas RJBencherif M Heterologous expression of human {alpha}6{beta}4{beta}3{alpha}5 nicotinic acetylcholine receptors: binding properties consistent with their natural expression require quaternary subunit assembly including the {alpha}5 subunit. J Pharmacol Exp Ther 312:619-26 (2005) [PubMed]  Article
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Cholinergic, Nicotinic Alpha6Beta3Beta4Alpha5
Name:Cholinergic, Nicotinic Alpha6Beta3Beta4Alpha5
Synonyms:n/a
Type:Enzyme Catalytic Domain
Mol. Mass.:51875.01
Organism:RAT
Description:Cholinergic, Nicotinic Alpha6Beta3Beta4Alpha5 0 RAT::P20420
Residue:452
Sequence:
MVQLLAGRWRPTGARRGTRGGLPELSSAAKHEDSLFRDLFEDYERWVRPVEHLSDKIKIK
FGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLRWNPDDYGGIKIIRVPSDSLWIPDIVL
FDNADGRFEGASTKTVVRYNGTVTWTQPANYKSSCTIDVTFFPFDLQNCSMKFGSWTYDG
SQVDIILEDQDVDRTDFFDNGEWEIMSAMGSKGNRTDSCCWYPYITYSFVIKRLPLFYTL
FLIIPCIGLSFLTVVVFYLPSNEGEKISLCTSVLVSLTVFLLVIEEIIPSSSKVIPLIGE
YLVFTMIFVTLSIMVTVFAINIHHRSSSTHNAMAPWVRKIFLHKLPKLLCMRSHADRYFT
QREEAESGAGPKSRNTLEAALDCIRYITRHVVKENDVREVVEDWKFIAQVLDRMFLWTFL
LVSIIGTLGLFVPVIYKWANIIVPVHIGNTIK
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  Blast E-value cutoff:
BDBM86241
n/a
NameBDBM86241
Synonyms:CAS_23255-54-1 | Dihydro-Beta-erythroidine | NSC_31762
TypeSmall organic molecule
Emp. Form.C16H21NO3
Mol. Mass.275.3428
SMILESCOC1CC=C2CCN3CCC4=C(CC(=O)OC4)C23C1 |t:4,11|
Structure
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