| Reaction Details |
|---|
 | Report a problem with these data |
| Target | cAMP-dependent protein kinase catalytic subunit beta |
|---|
| Ligand | BDBM14027 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 1600±n/a nM |
|---|
| Comments | PDSP_6133 |
|---|
| Citation |  Braverman, AS; Tibb, AS; Ruggieri, MR M2 and M3 muscarinic receptor activation of urinary bladder contractile signal transduction. I. Normal rat bladder. J Pharmacol Exp Ther316:869-74 (2006) [PubMed] Article |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| cAMP-dependent protein kinase catalytic subunit beta |
|---|
| Name: | cAMP-dependent protein kinase catalytic subunit beta |
|---|
| Synonyms: | KAPCB_RAT | PKA | Pkacb | Prkacb | cAMP-dependent protein kinase catalytic subunit beta |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 40715.41 |
|---|
| Organism: | RAT |
|---|
| Description: | PKA 0 RAT::P68182 |
|---|
| Residue: | 351 |
|---|
| Sequence: | MGNTAIAKKGSEVESVKEFLAKAKEDFLRKWENPPPSNAGLEDFERKKTLGTGSFGRVML
VKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKDNSNLYMV
MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGY
IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF
ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFAT
TDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEEIRVSITEKCGKEFCEF
|
|
|
|---|
| BDBM14027 |
|---|
| n/a |
|---|
| Name | BDBM14027 |
|---|
| Synonyms: | 5-(1,4-diazepan-1-ylsulfonyl)isoquinoline | 5-(1,4-diazepane-1-sulfonyl)isoquinoline | AT877 | CHEMBL38380 | CHEMBL541388 | Fasudil (HA-1077) | HA-1077 | US9687483, Fasudil | cid_163751 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H17N3O2S |
|---|
| Mol. Mass. | 291.369 |
|---|
| SMILES | O=S(=O)(N1CCCNCC1)c1cccc2cnccc12 |
|---|
| Structure | 
|
|---|
Search and Browse
