| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-1B adrenergic receptor |
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| Ligand | BDBM50033111 |
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| Substrate/Competitor | n/a |
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| Ki | 2±n/a nM |
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| Comments | PDSP_1798 |
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| Citation |  Kinsella, GK; Rozas, I; Watson, GW Computational study of antagonist/alpha1A adrenoceptor complexes--observations of conformational variations on the formation of ligand/receptor complexes. J Med Chem49:501-10 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Alpha-1B adrenergic receptor |
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| Name: | Alpha-1B adrenergic receptor |
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| Synonyms: | ADRA1B | Adra1b protein | adrenergic Alpha1B |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 50983.17 |
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| Organism: | Mus musculus |
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| Description: | Q05D47 |
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| Residue: | 462 |
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| Sequence: | MNPDLDTGHNTSAPAHWGELKDANFTGPNQTSSNSTLPQLDVTRAISVGLVLGAFILFAI
VGNILVILSVACNRHLRTPTNYFIVNLAIADLLLSFTVLPFSATLEVLGYWVLGRIFCDI
WAAVDVLCCTASILSLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGP
LLGWKEPAPNDDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAG
VMKEMSNSKELTLRIHSKNFHEDTLSSTKAKGHNPRSSIAVKLFKFSREKKAAKTLGIVV
GMFILCWLPFFIALPLGSLFSTLKPPDAVFKVVFWLGYFNSCLNPIIYPCSSKEFKRAFM
RILGCQCRGGRRRRRRRRLGGCAYTYRPWTRGGSLERSQSPKDSLDDSGSCMSGSQRTLP
SASPSPGYLGLGTQPPVELCASPEWKPGALLSLPEPPGRRGR
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| BDBM50033111 |
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| n/a |
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| Name | BDBM50033111 |
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| Synonyms: | 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetrahydro-2-furanyl)carbonyl)piperazine | 6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)piperazin-1-yl]quinazolin-4-amine | CHEMBL611 | TERAZOSIN | Terazosine |
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| Type | Small organic molecule |
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| Emp. Form. | C19H25N5O4 |
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| Mol. Mass. | 387.4329 |
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| SMILES | COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)C1CCCO1 |
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| Structure | 
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