| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine 3'-phospho 5'-phosphosulfate transporter 1 |
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| Ligand | BDBM86748 |
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| Substrate/Competitor | n/a |
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| Ki | >10000±n/a nM |
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| Comments | PDSP_7576 |
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| Citation |  Deecher, DC; Beyer, CE; Johnston, G; Bray, J; Shah, S; Abou-Gharbia, M; Andree, TH Desvenlafaxine succinate: A new serotonin and norepinephrine reuptake inhibitor. J Pharmacol Exp Ther318:657-65 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Adenosine 3'-phospho 5'-phosphosulfate transporter 1 |
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| Name: | Adenosine 3'-phospho 5'-phosphosulfate transporter 1 |
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| Synonyms: | Adenosine transporter | PAPS transporter 1 | PAPST1 | Putative MAPK-activating protein PM15 | Putative NF-kappa-B-activating protein 48 | S35B2_HUMAN | SLC35B2 | Solute carrier family 35 member B2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 47529.84 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q8TB61 |
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| Residue: | 432 |
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| Sequence: | MDARWWAVVVLAAFPSLGAGGETPEAPPESWTQLWFFRFVVNAAGYASFMVPGYLLVQYF
RRKNYLETGRGLCFPLVKACVFGNEPKASDEVPLAPRTEAAETTPMWQALKLLFCATGLQ
VSYLTWGVLQERVMTRSYGATATSPGERFTDSQFLVLMNRVLALIVAGLSCVLCKQPRHG
APMYRYSFASLSNVLSSWCQYEALKFVSFPTQVLAKASKVIPVMLMGKLVSRRSYEHWEY
LTATLISIGVSMFLLSSGPEPRSSPATTLSGLILLAGYIAFDSFTSNWQDALFAYKMSSV
QMMFGVNFFSCLFTVGSLLEQGALLEGTRFMGRHSEFAAHALLLSICSACGQLFIFYTIG
QFGAAVFTIIMTLRQAFAILLSCLLYGHTVTVVGGLGVAVVFAALLLRVYARGRLKQRGK
KAVPVESPVQKV
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| BDBM86748 |
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| n/a |
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| Name | BDBM86748 |
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| Synonyms: | CAS_386750-22-7 | Desvenlafaxine | NSC_6918664 | O-Desmethylvenlafaxine | US9944618, Compound ID No. 181 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H25NO2 |
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| Mol. Mass. | 263.3752 |
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| SMILES | CN(C)CC(c1ccc(O)cc1)C1(O)CCCCC1 |
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| Structure | 
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