| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 2 |
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| Ligand | BDBM86886 |
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| Substrate/Competitor | n/a |
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| Ki | 6600±n/a nM |
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| Comments | PDSP_8440 |
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| Citation |  Foloppe, N; Allen, NH; Bentley, CH; Brooks, TD; Kennett, G; Knight, AR; Leonardi, S; Misra, A; Monck, NJ; Sellwood, DM Discovery of a novel class of selective human CB1 inverse agonists. Bioorg Med Chem Lett18:1199-206 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Cannabinoid receptor 2 |
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| Name: | Cannabinoid receptor 2 |
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| Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 39690.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P34972 |
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| Residue: | 360 |
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| Sequence: | MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILS
SHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTAS
VGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCS
ELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLD
VRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYA
LRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
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| BDBM86886 |
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| n/a |
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| Name | BDBM86886 |
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| Synonyms: | CAS_15991674 | N-benzyl-5-(3,5-dimethylpiperidin-1-ylsulfonyl)-3-methylbenzofuran-2-carboxamide | NSC_15991674 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H28N2O4S |
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| Mol. Mass. | 440.555 |
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| SMILES | CC1CC(C)CN(C1)S(=O)(=O)c1ccc2oc(C(=O)NCc3ccccc3)c(C)c2c1 |
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| Structure | 
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