| Reaction Details |
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 | Report a problem with these data |
| Target | Mu-type opioid receptor |
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| Ligand | BDBM86952 |
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| Substrate/Competitor | n/a |
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| Ki | 22.9±n/a nM |
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| Comments | PDSP_8640 |
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| Citation |  Cunningham, CW; Mercer, SL; Hassan, HE; Traynor, JR; Eddington, ND; Coop, A Opioids and efflux transporters. Part 2: P-glycoprotein substrate activity of 3- and 6-substituted morphine analogs. J Med Chem51:2316-20 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Mu-type opioid receptor |
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| Name: | Mu-type opioid receptor |
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| Synonyms: | MOR-1 | MUOR1 | Mu-type opioid receptor (MOR) | OPIATE Mu | OPRM_RAT | Opiate non-selective | Opioid receptor B | Oprm1 | Ror-b |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44503.11 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the mu opioid receptor. |
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| Residue: | 398 |
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| Sequence: | MDSSTGPGNTSDCSDPLAQASCSPAPGSWLNLSHVDGNQSDPCGLNRTGLGGNDSLCPQT
GSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATST
LPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRT
PRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFA
FIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYV
IIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQ
QNSTRVRQNTREHPSTANTVDRTNHQLENLEAETAPLP
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| BDBM86952 |
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| n/a |
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| Name | BDBM86952 |
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| Synonyms: | 7,8-dihydro-3,6-didesoxymorphine | CAS_22816300 | NSC_22816300 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H21NO |
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| Mol. Mass. | 255.3547 |
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| SMILES | CN1CCC23C4CCCC2C1Cc1cccc(O4)c31 |TLB:8:9:1.2.3:11.12.18| |
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| Structure | 
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