| Reaction Details |
|---|
 | Report a problem with these data |
| Target | DNA dC->dU-editing enzyme APOBEC-3G |
|---|
| Ligand | BDBM839 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | SAR analysis of small molecule inhibitors of APOBEC3G DNA Deaminase via a fluorescence-based single-stranded DNA deaminase assay |
|---|
| Temperature | 298.15±n/a K |
|---|
| IC50 | >99000±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  PubChem, PC SAR analysis of small molecule inhibitors of APOBEC3G DNA Deaminase via a fluorescence-based single-stranded DNA deaminase assay PubChem Bioassay(2011)[AID] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| DNA dC->dU-editing enzyme APOBEC-3G |
|---|
| Name: | DNA dC->dU-editing enzyme APOBEC-3G |
|---|
| Synonyms: | ABC3G_HUMAN | APOBEC3G |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 46419.54 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | gi_13399304 |
|---|
| Residue: | 384 |
|---|
| Sequence: | MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPPLDAKIFRGQVYS
ELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATFLAEDPKVTLTIFV
ARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQRELFEPWNNLPK
YYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLNQRRG
FLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFSCAQEMAKFIS
KNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDHQGCPFQP
WDGLDEHSQDLSGRLRAILQNQEN
|
|
|
|---|
| BDBM839 |
|---|
| n/a |
|---|
| Name | BDBM839 |
|---|
| Synonyms: | cid_1741607 |
|---|
| Type | n/a |
|---|
| Emp. Form. | C20H17BrClF3N4O |
|---|
| Mol. Mass. | 501.727 |
|---|
| SMILES | FC(F)(F)c1cc(nc2c(Cl)c(nn12)C(=O)NC1CCCCC1)-c1ccc(Br)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
