| Reaction Details |
|---|
 | Report a problem with these data |
| Target | DNA dC->dU-editing enzyme APOBEC-3G |
|---|
| Ligand | BDBM87081 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | SAR analysis of small molecule inhibitors of APOBEC3G DNA Deaminase via a fluorescence-based single-stranded DNA deaminase assay |
|---|
| Temperature | 298.15±n/a K |
|---|
| IC50 | >99000±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  PubChem, PC SAR analysis of small molecule inhibitors of APOBEC3G DNA Deaminase via a fluorescence-based single-stranded DNA deaminase assay PubChem Bioassay(2011)[AID] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| DNA dC->dU-editing enzyme APOBEC-3G |
|---|
| Name: | DNA dC->dU-editing enzyme APOBEC-3G |
|---|
| Synonyms: | ABC3G_HUMAN | APOBEC3G |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 46419.54 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | gi_13399304 |
|---|
| Residue: | 384 |
|---|
| Sequence: | MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPPLDAKIFRGQVYS
ELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATFLAEDPKVTLTIFV
ARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQRELFEPWNNLPK
YYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLNQRRG
FLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFSCAQEMAKFIS
KNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDHQGCPFQP
WDGLDEHSQDLSGRLRAILQNQEN
|
|
|
|---|
| BDBM87081 |
|---|
| n/a |
|---|
| Name | BDBM87081 |
|---|
| Synonyms: | 4-N-(4-ethylphenyl)-2-N-(4-methoxyphenyl)-6-pyrrolidin-1-yl-1,3,5-triazine-2,4-diamine;hydron;chloride | MLS-0463512.0001 | N4-(4-ethylphenyl)-N2-(4-methoxyphenyl)-6-(1-pyrrolidinyl)-1,3,5-triazine-2,4-diamine;hydron;chloride | N4-(4-ethylphenyl)-N2-(4-methoxyphenyl)-6-pyrrolidin-1-yl-1,3,5-triazine-2,4-diamine;hydron;chloride | [4-(4-ethylanilino)-6-pyrrolidino-s-triazin-2-yl]-(4-methoxyphenyl)amine;hydron;chloride | cid_53301986 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H26N6O |
|---|
| Mol. Mass. | 390.4814 |
|---|
| SMILES | CCc1ccc(Nc2nc(Nc3ccc(OC)cc3)nc(n2)N2CCCC2)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
