| Reaction Details |
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 | Report a problem with these data |
| Target | Tegument protein VP16 |
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| Ligand | BDBM87286 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3) |
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| IC50 | 7445±n/a nM |
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| Citation |  PubChem, PC Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3): Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16) PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Tegument protein VP16 |
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| Name: | Tegument protein VP16 |
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| Synonyms: | Alpha trans-inducing protein (VP16) | VP16_HHV11 | transactivating tegument protein VP16 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 54325.13 |
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| Organism: | Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus1) |
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| Description: | EBI_100271 |
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| Residue: | 490 |
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| Sequence: | MDLLVDELFADMNADGASPPPPRPAGGPKNTPAAPPLYATGRLSQAQLMPSPPMPVPPAA
LFNRLLDDLGFSAGPALCTMLDTWNEDLFSALPTNADLYRECKFLSTLPSDVVEWGDAYV
PERTQIDIRAHGDVAFPTLPATRDGLGLYYEALSRFFHAELRAREESYRTVLANFCSALY
RYLRASVRQLHRQAHMRGRDRDLGEMLRATIADRYYRETARLARVLFLHLYLFLTREILW
AAYAEQMMRPDLFDCLCCDLESWRQLAGLFQPFMFVNGALTVRGVPIEARRLRELNHIRE
HLNLPLVRSAATEEPGAPLTTPPTLHGNQARASGYFMVLIRAKLDSYSSFTTSPSEAVMR
EHAYSRARTKNNYGSTIEGLLDLPDDDAPEEAGLAAPRLSFLPAGHTRRLSTAPPTDVSL
GDELHLDGEDVAMAHADALDDFDLDMLGDGDSPGPGFTPHDSAPYGALDMADFEFEQMFT
DALGIDEYGG
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| BDBM87286 |
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| n/a |
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| Name | BDBM87286 |
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| Synonyms: | 4-(2-fluorophenyl)-3-(3-imidazol-1-ylpropyl)-N-pyridin-3-yl-1,3-thiazol-2-imine | 4-(2-fluorophenyl)-3-[3-(1-imidazolyl)propyl]-N-(3-pyridinyl)-2-thiazolimine | MLS000418005 | SMR000264872 | [4-(2-fluorophenyl)-3-(3-imidazol-1-ylpropyl)-4-thiazolin-2-ylidene]-(3-pyridyl)amine | cid_4216155 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H18FN5S |
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| Mol. Mass. | 379.454 |
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| SMILES | Fc1ccccc1-c1cs\c(=N/c2cccnc2)n1CCCn1ccnc1 |
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| Structure | 
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