| Reaction Details |
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 | Report a problem with these data |
| Target | Tegument protein VP16 |
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| Ligand | BDBM64729 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3) |
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| IC50 | 4780±n/a nM |
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| Citation |  PubChem, PC Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3): Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16) PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Tegument protein VP16 |
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| Name: | Tegument protein VP16 |
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| Synonyms: | Alpha trans-inducing protein (VP16) | VP16_HHV11 | transactivating tegument protein VP16 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 54325.13 |
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| Organism: | Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus1) |
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| Description: | EBI_100271 |
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| Residue: | 490 |
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| Sequence: | MDLLVDELFADMNADGASPPPPRPAGGPKNTPAAPPLYATGRLSQAQLMPSPPMPVPPAA
LFNRLLDDLGFSAGPALCTMLDTWNEDLFSALPTNADLYRECKFLSTLPSDVVEWGDAYV
PERTQIDIRAHGDVAFPTLPATRDGLGLYYEALSRFFHAELRAREESYRTVLANFCSALY
RYLRASVRQLHRQAHMRGRDRDLGEMLRATIADRYYRETARLARVLFLHLYLFLTREILW
AAYAEQMMRPDLFDCLCCDLESWRQLAGLFQPFMFVNGALTVRGVPIEARRLRELNHIRE
HLNLPLVRSAATEEPGAPLTTPPTLHGNQARASGYFMVLIRAKLDSYSSFTTSPSEAVMR
EHAYSRARTKNNYGSTIEGLLDLPDDDAPEEAGLAAPRLSFLPAGHTRRLSTAPPTDVSL
GDELHLDGEDVAMAHADALDDFDLDMLGDGDSPGPGFTPHDSAPYGALDMADFEFEQMFT
DALGIDEYGG
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| BDBM64729 |
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| n/a |
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| Name | BDBM64729 |
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| Synonyms: | MLS001212967 | N-[(2,4-dichlorophenyl)-(8-hydroxy-7-quinolinyl)methyl]pentanamide | N-[(2,4-dichlorophenyl)-(8-hydroxy-7-quinolyl)methyl]valeramide | N-[(2,4-dichlorophenyl)-(8-hydroxyquinolin-7-yl)methyl]pentanamide | N-[(2,4-dichlorophenyl)-(8-oxidanylquinolin-7-yl)methyl]pentanamide | Pentanoic acid [(2,4-dichloro-phenyl)-(8-hydroxy-quinolin-7-yl)-methyl]-amide | SMR000517136 | cid_2922048 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H20Cl2N2O2 |
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| Mol. Mass. | 403.302 |
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| SMILES | CCCCC(=O)NC(c1ccc(Cl)cc1Cl)c1ccc2cccnc2c1O |
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| Structure | 
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