| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Tegument protein VP16 |
|---|
| Ligand | BDBM59548 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3) |
|---|
| IC50 | 1199±n/a nM |
|---|
| Citation |  PubChem, PC Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3): Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16) PubChem Bioassay(2012)[AID] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Tegument protein VP16 |
|---|
| Name: | Tegument protein VP16 |
|---|
| Synonyms: | Alpha trans-inducing protein (VP16) | VP16_HHV11 | transactivating tegument protein VP16 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 54325.13 |
|---|
| Organism: | Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus1) |
|---|
| Description: | EBI_100271 |
|---|
| Residue: | 490 |
|---|
| Sequence: | MDLLVDELFADMNADGASPPPPRPAGGPKNTPAAPPLYATGRLSQAQLMPSPPMPVPPAA
LFNRLLDDLGFSAGPALCTMLDTWNEDLFSALPTNADLYRECKFLSTLPSDVVEWGDAYV
PERTQIDIRAHGDVAFPTLPATRDGLGLYYEALSRFFHAELRAREESYRTVLANFCSALY
RYLRASVRQLHRQAHMRGRDRDLGEMLRATIADRYYRETARLARVLFLHLYLFLTREILW
AAYAEQMMRPDLFDCLCCDLESWRQLAGLFQPFMFVNGALTVRGVPIEARRLRELNHIRE
HLNLPLVRSAATEEPGAPLTTPPTLHGNQARASGYFMVLIRAKLDSYSSFTTSPSEAVMR
EHAYSRARTKNNYGSTIEGLLDLPDDDAPEEAGLAAPRLSFLPAGHTRRLSTAPPTDVSL
GDELHLDGEDVAMAHADALDDFDLDMLGDGDSPGPGFTPHDSAPYGALDMADFEFEQMFT
DALGIDEYGG
|
|
|
|---|
| BDBM59548 |
|---|
| n/a |
|---|
| Name | BDBM59548 |
|---|
| Synonyms: | 3-(4-chlorophenyl)-6-(4-fluorophenyl)-5-methyl-7-pyrazolo[1,5-a]pyrimidinamine | 3-(4-chlorophenyl)-6-(4-fluorophenyl)-5-methyl-pyrazolo[1,5-a]pyrimidin-7-amine | 3-(4-chlorophenyl)-6-(4-fluorophenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-amine | MLS001165929 | SMR000550192 | [3-(4-chlorophenyl)-6-(4-fluorophenyl)-5-methyl-pyrazolo[1,5-a]pyrimidin-7-yl]amine | cid_1474387 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H14ClFN4 |
|---|
| Mol. Mass. | 352.793 |
|---|
| SMILES | Cc1nc2c(cnn2c(N)c1-c1ccc(F)cc1)-c1ccc(Cl)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
