| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Tegument protein VP16 |
|---|
| Ligand | BDBM87350 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3) |
|---|
| IC50 | 3368±n/a nM |
|---|
| Citation |  PubChem, PC Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3): Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16) PubChem Bioassay(2012)[AID] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Tegument protein VP16 |
|---|
| Name: | Tegument protein VP16 |
|---|
| Synonyms: | Alpha trans-inducing protein (VP16) | VP16_HHV11 | transactivating tegument protein VP16 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 54325.13 |
|---|
| Organism: | Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus1) |
|---|
| Description: | EBI_100271 |
|---|
| Residue: | 490 |
|---|
| Sequence: | MDLLVDELFADMNADGASPPPPRPAGGPKNTPAAPPLYATGRLSQAQLMPSPPMPVPPAA
LFNRLLDDLGFSAGPALCTMLDTWNEDLFSALPTNADLYRECKFLSTLPSDVVEWGDAYV
PERTQIDIRAHGDVAFPTLPATRDGLGLYYEALSRFFHAELRAREESYRTVLANFCSALY
RYLRASVRQLHRQAHMRGRDRDLGEMLRATIADRYYRETARLARVLFLHLYLFLTREILW
AAYAEQMMRPDLFDCLCCDLESWRQLAGLFQPFMFVNGALTVRGVPIEARRLRELNHIRE
HLNLPLVRSAATEEPGAPLTTPPTLHGNQARASGYFMVLIRAKLDSYSSFTTSPSEAVMR
EHAYSRARTKNNYGSTIEGLLDLPDDDAPEEAGLAAPRLSFLPAGHTRRLSTAPPTDVSL
GDELHLDGEDVAMAHADALDDFDLDMLGDGDSPGPGFTPHDSAPYGALDMADFEFEQMFT
DALGIDEYGG
|
|
|
|---|
| BDBM87350 |
|---|
| n/a |
|---|
| Name | BDBM87350 |
|---|
| Synonyms: | 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-2-oxolanyl]-3H-purine-6-thione | 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purine-6-thione | 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methylol-tetrahydrofuran-2-yl]-3H-purine-6-thione | 2-azanyl-9-[(2R,3R,4S,5R)-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl]-3H-purine-6-thione | MLS002153781 | SMR001233165 | Thioguanosine | cid_2724387 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C10H13N5O4S |
|---|
| Mol. Mass. | 299.306 |
|---|
| SMILES | Nc1nc2n(cnc2c(=S)[nH]1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O |
|---|
| Structure | 
|
|---|
Search and Browse
