BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetHigh-affinity choline transporter
LigandBDBM87573
Substrate/Competitorn/a
Meas. Tech.JHICC_CHT_Inh_3H uptake_CRC
IC50 12788.0182±n/a nM
Citation PubChem PC JHICC_CHT_Inh_3H uptake_CRC PubChem Bioassay (2012)[AID]  Article
More Info.:Get all data from this article,  Assay Method
 
High-affinity choline transporter
Name:High-affinity choline transporter
Synonyms:high affinity choline transporter 1
Type:PROTEIN
Mol. Mass.:63194.33
Organism:Homo sapiens (Human)
Description:ChEMBL_1464247
Residue:580
Sequence:
MAFHVEGLIAIIVFYLLILLVGIWAAWRTKNSGSAEERSEAIIVGGRDIGLLVGGFTMTA
TWVGGGYINGTAEAVYVPGYGLAWAQAPIGYSLSLILGGLFFAKPMRSKGYVTMLDPFQQ
IYGKRMGGLLFIPALMGEMFWAAAIFSALGATISVIIDVDMHISVIISALIATLYTLVGG
LYSVAYTDVVQLFCIFVGLWISVPFALSHPAVADIGFTAVHAKYQKPWLGTVDSSEVYSW
LDSFLLLMLGGIPWQAYFQRVLSSSSATYAQVLSFLAAFGCLVMAIPAILIGAIGASTDW
NQTAYGLPDPKTTEEADMILPIVLQYLCPVYISFFGLGAVSAAVMSSADSSILSASSMFA
RNIYQLSFRQNASDKEIVWVMRITVFVFGASATAMALLTKTVYGLWYLSSDLVYIVIFPQ
LLCVLFVKGTNTYGAVAGYVSGLFLRITGGEPYLYLQPLIFYPGYYPDDNGIYNQKFPFK
TLAMVTSFLTNICISYLAKYLFESGTLPPKLDVFDAVVARHSEENMDKTILVKNENIKLD
ELALVKPRQSMTLSSTFTNKEAFLDVDSSPEGSGTEDNLQ
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM87573
n/a
NameBDBM87573
Synonyms:2,4-Dichloro-N-[4-(pyridin-2-ylsulfamoyl)-phenyl]-benzamide | 2,4-bis(chloranyl)-N-[4-(pyridin-2-ylsulfamoyl)phenyl]benzamide | 2,4-dichloro-N-[4-(2-pyridinylsulfamoyl)phenyl]benzamide | 2,4-dichloro-N-[4-(2-pyridylsulfamoyl)phenyl]benzamide | 2,4-dichloro-N-[4-(pyridin-2-ylsulfamoyl)phenyl]benzamide | MLS001223293 | SMR000612077 | cid_1078173
TypeSmall organic molecule
Emp. Form.C18H13Cl2N3O3S
Mol. Mass.422.285
SMILESClc1ccc(C(=O)Nc2ccc(cc2)S(=O)(=O)Nc2ccccn2)c(Cl)c1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: