| Reaction Details |
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 | Report a problem with these data |
| Target | Polyadenylate-binding protein 1 |
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| Ligand | BDBM34314 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose-response secondary confirmation of microRNA-mediated mRNA deadenylation inhibitors by fluoresence polarization assay using Cy5 labeled peptide |
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| IC50 | >66000±n/a nM |
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| Citation |  PubChem, PC Dose-response secondary confirmation of microRNA-mediated mRNA deadenylation inhibitors by fluoresence polarization assay using Cy5 labeled peptide PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Polyadenylate-binding protein 1 |
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| Name: | Polyadenylate-binding protein 1 |
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| Synonyms: | PAB1 | PABP | PABP1 | PABP1_HUMAN | PABPC1 | PABPC2 | poly(A) binding protein, cytoplasmic 1 | polyadenylate-binding protein 1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 70694.26 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_46367787 |
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| Residue: | 636 |
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| Sequence: | MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQ
QPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFS
AFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKERE
AELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFER
HEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKN
LDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVAT
KPLYVALAQRKEERQAHLTNQYMQRMASVRAVPNPVINPYQPAPPSGYFMAAIPQTQNRA
AYYPPSQIAQLRPSPRWTAQGARPHPFQNMPGAIRPAAPRPPFSTMRPASSQVPRVMSTQ
RVANTSTQTMGPRPAAAAAAATPAVRTVPQYKYAAGVRNPQQHLNAQPQVTMQQPAVHVQ
GQEPLTASMLASAPPQEQKQMLGERLFPLIQAMHPTLAGKITGMLLEIDNSELLHMLESP
ESLRSKVDEAVAVLQAHQAKEAAQKAVNSATGVPTV
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| BDBM34314 |
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| n/a |
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| Name | BDBM34314 |
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| Synonyms: | MLS000054793 | SMR000060267 | bis(1-methyl-2-imidazolyl)-(4-morpholinyl)-sulfanylidenephosphorane | bis(1-methylimidazol-2-yl)-morpholin-4-yl-sulfanylidene--phosphane | bis(1-methylimidazol-2-yl)-morpholino-thioxo-phosphorane | cid_2997661 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H18N5OPS |
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| Mol. Mass. | 311.343 |
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| SMILES | Cn1ccnc1P(=S)(N1CCOCC1)c1nccn1C |
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| Structure | 
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