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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Prothrombin | ||
| Ligand | BDBM78566 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Dose Response validation of uHTS RPN11 inhibitor hits using a Thrombin Fluorescence Polarization assay | ||
| IC50 | 16000±7890 nM | ||
| Citation |  PubChem, PC Dose Response validation of uHTS RPN11 inhibitor hits using a Thrombin Fluorescence Polarization assay PubChem Bioassay(2012)[AID] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Prothrombin | |||
| Name: | Prothrombin | ||
| Synonyms: | Activation peptide fragment 1 | Activation peptide fragment 2 | Coagulation factor II | F2 | Prothrombin | THRB_BOVIN | Thrombin | Thrombin heavy chain | Thrombin light chain | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 70502.73 | ||
| Organism: | Bos taurus (Bovine) | ||
| Description: | P00735 | ||
| Residue: | 625 | ||
| Sequence: |
| ||
| BDBM78566 | |||
| n/a | |||
| Name | BDBM78566 | ||
| Synonyms: | 2-(1-benzylindol-3-yl)-7-methyl-1,2,3,5,6,8-hexahydropyrido[2,3]thieno[2,4-d]pyrimidin-4-one | 7-methyl-2-[1-(phenylmethyl)-3-indolyl]-1,2,3,5,6,8-hexahydropyrido[2,3]thieno[2,4-d]pyrimidin-4-one | 7-methyl-2-[1-(phenylmethyl)indol-3-yl]-1,2,3,5,6,8-hexahydropyrido[2,3]thieno[2,4-d]pyrimidin-4-one | MLS000114183 | SMR000035376 | cid_660805 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C25H24N4OS | ||
| Mol. Mass. | 428.549 | ||
| SMILES | CN1CCc2c(C1)sc1NC(NC(=O)c21)c1cn(Cc2ccccc2)c2ccccc12 | ||
| Structure | 
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