Ki Summary

Reaction Details

Report a problem with these data

Target

Tyrosine-protein phosphatase non-receptor type 5

Ligand

BDBM88730

Substrate/Competitor

n/a

Meas. Tech.

Dose response confirmation of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a fluorescence intensity assay

IC50

6730±n/a nM

Citation

PubChem, PC Dose response confirmation of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a fluorescence intensity assay PubChem Bioassay(2012)[AID]

More Info.:

Get all data from this article, Assay Method

Tyrosine-protein phosphatase non-receptor type 5

Name:

Tyrosine-protein phosphatase non-receptor type 5

Synonyms:

PTN5_HUMAN | PTPN5 | Tyrosine-protein phosphatase non-receptor type 5 | Tyrosine-protein phosphatase non-receptor type 5 isoform a

Type:

Enzyme Catalytic Domain

Mol. Mass.:

63510.68

Organism:

Homo sapiens (Human)

Description:

gi_90652859

Residue:

565

Sequence:

MNYEGARSERENHAADDSEGGALDMCCSERLPGLPQPIVMEALDEAEGLQDSQREMPPPP
PPSPPSDPAQKPPPRGAGSHSLTVRSSLCLFAASQFLLACGVLWFSGYGHIWSQNATNLV
SSLLTLLKQLEPTAWLDSGTWGVPSLLLVFLSVGLVLVTTLVWHLLRTPPEPPTPLPPED
RRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTVKSMGLQ
ERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRVLQAEELHEKALDPFLL
QAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIR
GYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYD
GVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEE
AAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQ
TCEQYQFVHHVMSLYEKQLSHQSPE

BDBM88730

n/a

Name

BDBM88730

Synonyms:

MLS000574482 | N-[5-(1H-benzimidazol-2-yl)-2-chloranyl-phenyl]-4-ethoxy-3-nitro-benzamide | N-[5-(1H-benzimidazol-2-yl)-2-chloro-phenyl]-4-ethoxy-3-nitro-benzamide | N-[5-(1H-benzimidazol-2-yl)-2-chlorophenyl]-4-ethoxy-3-nitrobenzamide | SMR000195146 | cid_1338419

Type

Small organic molecule

Emp. Form.

C22H17ClN4O4

Mol. Mass.

436.848

SMILES

CCOc1ccc(cc1[N+]([O-])=O)C(=O)Nc1cc(ccc1Cl)-c1nc2ccccc2[nH]1

Structure