Ki Summary

Reaction Details

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Target

Tyrosine-protein phosphatase non-receptor type 5

Ligand

BDBM88735

Substrate/Competitor

n/a

Meas. Tech.

Dose response confirmation of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a fluorescence intensity assay

IC50

>80000±n/a nM

Citation

PubChem, PC Dose response confirmation of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a fluorescence intensity assay PubChem Bioassay(2012)[AID]

More Info.:

Get all data from this article, Assay Method

Tyrosine-protein phosphatase non-receptor type 5

Name:

Tyrosine-protein phosphatase non-receptor type 5

Synonyms:

PTN5_HUMAN | PTPN5 | Tyrosine-protein phosphatase non-receptor type 5 | Tyrosine-protein phosphatase non-receptor type 5 isoform a

Type:

Enzyme Catalytic Domain

Mol. Mass.:

63510.68

Organism:

Homo sapiens (Human)

Description:

gi_90652859

Residue:

565

Sequence:

MNYEGARSERENHAADDSEGGALDMCCSERLPGLPQPIVMEALDEAEGLQDSQREMPPPP
PPSPPSDPAQKPPPRGAGSHSLTVRSSLCLFAASQFLLACGVLWFSGYGHIWSQNATNLV
SSLLTLLKQLEPTAWLDSGTWGVPSLLLVFLSVGLVLVTTLVWHLLRTPPEPPTPLPPED
RRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTVKSMGLQ
ERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRVLQAEELHEKALDPFLL
QAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIR
GYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYD
GVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEE
AAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQ
TCEQYQFVHHVMSLYEKQLSHQSPE

BDBM88735

n/a

Name

BDBM88735

Synonyms:

1-(2-methoxyethyl)-1-(1-pyridin-3-ylethyl)-3-(2,4,6-trimethylphenyl)thiourea | 1-(2-methoxyethyl)-1-[1-(3-pyridinyl)ethyl]-3-(2,4,6-trimethylphenyl)thiourea | 3-mesityl-1-(2-methoxyethyl)-1-[1-(3-pyridyl)ethyl]thiourea | MLS000584539 | N'-mesityl-N-(2-methoxyethyl)-N-(1-pyridin-3-ylethyl)thiourea | SMR000207125 | cid_4105237

Type

Small organic molecule

Emp. Form.

C20H27N3OS

Mol. Mass.

357.513

SMILES

COCCN(C(C)c1cccnc1)C(=S)Nc1c(C)cc(C)cc1C

Structure