| Reaction Details |
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 | Report a problem with these data |
| Target | Tyrosine-protein phosphatase non-receptor type 5 |
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| Ligand | BDBM88736 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response confirmation of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a fluorescence intensity assay |
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| IC50 | 27200±n/a nM |
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| Citation |  PubChem, PC Dose response confirmation of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a fluorescence intensity assay PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Tyrosine-protein phosphatase non-receptor type 5 |
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| Name: | Tyrosine-protein phosphatase non-receptor type 5 |
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| Synonyms: | PTN5_HUMAN | PTPN5 | Tyrosine-protein phosphatase non-receptor type 5 | Tyrosine-protein phosphatase non-receptor type 5 isoform a |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 63510.68 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_90652859 |
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| Residue: | 565 |
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| Sequence: | MNYEGARSERENHAADDSEGGALDMCCSERLPGLPQPIVMEALDEAEGLQDSQREMPPPP
PPSPPSDPAQKPPPRGAGSHSLTVRSSLCLFAASQFLLACGVLWFSGYGHIWSQNATNLV
SSLLTLLKQLEPTAWLDSGTWGVPSLLLVFLSVGLVLVTTLVWHLLRTPPEPPTPLPPED
RRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTVKSMGLQ
ERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRVLQAEELHEKALDPFLL
QAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIR
GYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYD
GVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEE
AAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQ
TCEQYQFVHHVMSLYEKQLSHQSPE
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| BDBM88736 |
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| n/a |
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| Name | BDBM88736 |
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| Synonyms: | MLS000584580 | N-(3-chloranyl-4-methoxy-phenyl)-4-[methyl(oxolan-2-ylmethyl)amino]piperidine-1-carbothioamide | N-(3-chloro-4-methoxy-phenyl)-4-[methyl(tetrahydrofurfuryl)amino]piperidine-1-carbothioamide | N-(3-chloro-4-methoxyphenyl)-4-[methyl(2-oxolanylmethyl)amino]-1-piperidinecarbothioamide | N-(3-chloro-4-methoxyphenyl)-4-[methyl(oxolan-2-ylmethyl)amino]piperidine-1-carbothioamide | N-(3-chloro-4-methoxyphenyl)-4-[methyl(tetrahydrofuran-2-ylmethyl)amino]piperidine-1-carbothioamide | SMR000207165 | cid_4112942 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H28ClN3O2S |
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| Mol. Mass. | 397.963 |
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| SMILES | COc1ccc(NC(=S)N2CCC(CC2)N(C)CC2CCCO2)cc1Cl |
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| Structure | 
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