| Reaction Details |
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 | Report a problem with these data |
| Target | Tyrosine-protein phosphatase non-receptor type 5 |
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| Ligand | BDBM52621 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response confirmation of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a fluorescence intensity assay |
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| IC50 | 25500±n/a nM |
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| Citation |  PubChem, PC Dose response confirmation of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a fluorescence intensity assay PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Tyrosine-protein phosphatase non-receptor type 5 |
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| Name: | Tyrosine-protein phosphatase non-receptor type 5 |
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| Synonyms: | PTN5_HUMAN | PTPN5 | Tyrosine-protein phosphatase non-receptor type 5 | Tyrosine-protein phosphatase non-receptor type 5 isoform a |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 63510.68 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_90652859 |
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| Residue: | 565 |
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| Sequence: | MNYEGARSERENHAADDSEGGALDMCCSERLPGLPQPIVMEALDEAEGLQDSQREMPPPP
PPSPPSDPAQKPPPRGAGSHSLTVRSSLCLFAASQFLLACGVLWFSGYGHIWSQNATNLV
SSLLTLLKQLEPTAWLDSGTWGVPSLLLVFLSVGLVLVTTLVWHLLRTPPEPPTPLPPED
RRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTVKSMGLQ
ERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRVLQAEELHEKALDPFLL
QAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIR
GYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYD
GVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEE
AAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQ
TCEQYQFVHHVMSLYEKQLSHQSPE
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| BDBM52621 |
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| n/a |
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| Name | BDBM52621 |
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| Synonyms: | (4Z)-4-(4-hydroxy-3-methoxy-5-nitro-benzylidene)-1-(m-tolyl)pyrazolidine-3,5-quinone | (4Z)-4-[(3-methoxy-5-nitro-4-oxidanyl-phenyl)methylidene]-1-(3-methylphenyl)pyrazolidine-3,5-dione | (4Z)-4-[(4-hydroxy-3-methoxy-5-nitrophenyl)methylidene]-1-(3-methylphenyl)pyrazolidine-3,5-dione | 4-(4-hydroxy-3-methoxy-5-nitrobenzylidene)-1-(3-methylphenyl)-3,5-pyrazolidinedione | MLS000626744 | SMR000299131 | cid_2176498 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H15N3O6 |
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| Mol. Mass. | 369.3282 |
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| SMILES | COc1cc(\C=C2\C(=O)NN(C2=O)c2cccc(C)c2)cc(c1O)[N+]([O-])=O |
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| Structure | 
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