Ki Summary

Reaction Details

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Target

Tyrosine-protein phosphatase non-receptor type 5

Ligand

BDBM88777

Substrate/Competitor

n/a

Meas. Tech.

Dose response confirmation of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a fluorescence intensity assay

IC50

>80000±n/a nM

Citation

PubChem, PC Dose response confirmation of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a fluorescence intensity assay PubChem Bioassay(2012)[AID]

More Info.:

Get all data from this article, Assay Method

Tyrosine-protein phosphatase non-receptor type 5

Name:

Tyrosine-protein phosphatase non-receptor type 5

Synonyms:

PTN5_HUMAN | PTPN5 | Tyrosine-protein phosphatase non-receptor type 5 | Tyrosine-protein phosphatase non-receptor type 5 isoform a

Type:

Enzyme Catalytic Domain

Mol. Mass.:

63510.68

Organism:

Homo sapiens (Human)

Description:

gi_90652859

Residue:

565

Sequence:

MNYEGARSERENHAADDSEGGALDMCCSERLPGLPQPIVMEALDEAEGLQDSQREMPPPP
PPSPPSDPAQKPPPRGAGSHSLTVRSSLCLFAASQFLLACGVLWFSGYGHIWSQNATNLV
SSLLTLLKQLEPTAWLDSGTWGVPSLLLVFLSVGLVLVTTLVWHLLRTPPEPPTPLPPED
RRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTVKSMGLQ
ERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRVLQAEELHEKALDPFLL
QAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIR
GYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYD
GVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEE
AAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQ
TCEQYQFVHHVMSLYEKQLSHQSPE

BDBM88777

n/a

Name

BDBM88777

Synonyms:

4-[5-(2,5-dichlorophenyl)-1,2,4-oxadiazol-3-yl]pyridine | 5-(2,5-dichlorophenyl)-3-(4-pyridyl)-1,2,4-oxadiazole | 5-(2,5-dichlorophenyl)-3-pyridin-4-yl-1,2,4-oxadiazole | 5-[2,5-bis(chloranyl)phenyl]-3-pyridin-4-yl-1,2,4-oxadiazole | MLS001000871 | SMR000497742 | cid_895032

Type

Small organic molecule

Emp. Form.

C13H7Cl2N3O

Mol. Mass.

292.12

SMILES

Clc1ccc(Cl)c(c1)-c1nc(no1)-c1ccncc1

Structure