Reaction Details |
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Target | Dual specificity protein phosphatase 3 |
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Ligand | BDBM82647 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay |
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IC50 | 1810±n/a nM |
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Citation | PubChem, PC Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay PubChem Bioassay(2012)[AID] |
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More Info.: | Get all data from this article, Assay Method |
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Dual specificity protein phosphatase 3 |
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Name: | Dual specificity protein phosphatase 3 |
Synonyms: | DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR |
Type: | Hydrolase |
Mol. Mass.: | 20480.58 |
Organism: | Homo sapiens (Human) |
Description: | n/a |
Residue: | 185 |
Sequence: | MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVL
NAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRV
LVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKE
GKLKP
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BDBM82647 |
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n/a |
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Name | BDBM82647 |
Synonyms: | 2-(1H-benzimidazol-2-ylsulfanyl)-1-(2,3-dimethylindol-1-yl)ethanone | 2-(1H-benzimidazol-2-ylthio)-1-(2,3-dimethyl-1-indolyl)ethanone | 2-(1H-benzimidazol-2-ylthio)-1-(2,3-dimethylindol-1-yl)ethanone | 2-{[2-(2,3-dimethyl-1H-indol-1-yl)-2-oxoethyl]thio}-1H-benzimidazole | MLS000535320 | SMR000142756 | cid_704124 |
Type | Small organic molecule |
Emp. Form. | C19H17N3OS |
Mol. Mass. | 335.423 |
SMILES | Cc1c(C)c2ccccc2n1C(=O)CSc1nc2ccccc2[nH]1 |
Structure |
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