| Reaction Details |
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 | Report a problem with these data |
| Target | Dual specificity protein phosphatase 3 |
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| Ligand | BDBM50431 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay |
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| IC50 | 2290±n/a nM |
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| Citation |  PubChem, PC Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Dual specificity protein phosphatase 3 |
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| Name: | Dual specificity protein phosphatase 3 |
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| Synonyms: | DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR |
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| Type: | Hydrolase |
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| Mol. Mass.: | 20480.58 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 185 |
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| Sequence: | MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVL
NAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRV
LVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKE
GKLKP
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| BDBM50431 |
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| n/a |
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| Name | BDBM50431 |
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| Synonyms: | (5Z)-2-azanylidene-3-(4-fluorophenyl)-5-[(4-hydroxyphenyl)methylidene]-1,3-thiazolidin-4-one | (5Z)-3-(4-fluorophenyl)-5-(4-hydroxybenzylidene)-2-imino-thiazolidin-4-one | (5Z)-3-(4-fluorophenyl)-5-[(4-hydroxyphenyl)methylidene]-2-imino-1,3-thiazolidin-4-one | (5Z)-3-(4-fluorophenyl)-5-[(4-hydroxyphenyl)methylidene]-2-imino-4-thiazolidinone | 3-(4-fluorophenyl)-5-(4-hydroxybenzylidene)-2-imino-1,3-thiazolidin-4-one | MLS000676410 | SMR000298434 | cid_1258959 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H11FN2O2S |
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| Mol. Mass. | 314.334 |
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| SMILES | Oc1ccc(\C=C2/SC(=N)N(C2=O)c2ccc(F)cc2)cc1 |
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| Structure | 
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