| Reaction Details |
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 | Report a problem with these data |
| Target | Dual specificity protein phosphatase 3 |
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| Ligand | BDBM81080 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay |
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| IC50 | 740±n/a nM |
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| Citation |  PubChem, PC Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Dual specificity protein phosphatase 3 |
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| Name: | Dual specificity protein phosphatase 3 |
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| Synonyms: | DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR |
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| Type: | Hydrolase |
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| Mol. Mass.: | 20480.58 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 185 |
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| Sequence: | MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVL
NAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRV
LVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKE
GKLKP
|
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|
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| BDBM81080 |
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| n/a |
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| Name | BDBM81080 |
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| Synonyms: | 4-[(4-ethyl-1-piperazinyl)-mercaptomethylidene]-1-cyclohexa-2,5-dienone | 4-[(4-ethyl-1-piperazinyl)carbonothioyl]phenol | 4-[(4-ethylpiperazin-1-yl)-sulfanyl-methylidene]cyclohexa-2,5-dien-1-one | 4-[(4-ethylpiperazin-1-yl)-sulfanylmethylidene]cyclohexa-2,5-dien-1-one | 4-[(4-ethylpiperazino)-mercapto-methylene]cyclohexa-2,5-dien-1-one | MLS000621546 | SMR000299713 | US11225469, Compound 15 | cid_5424195 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H18N2OS |
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| Mol. Mass. | 250.36 |
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| SMILES | CCN1CCN(CC1)C(=S)c1ccc(O)cc1 |
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| Structure | 
|
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