| Reaction Details |
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 | Report a problem with these data |
| Target | Dual specificity protein phosphatase 3 |
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| Ligand | BDBM88769 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay |
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| IC50 | 500±n/a nM |
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| Citation |  PubChem, PC Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Dual specificity protein phosphatase 3 |
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| Name: | Dual specificity protein phosphatase 3 |
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| Synonyms: | DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR |
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| Type: | Hydrolase |
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| Mol. Mass.: | 20480.58 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 185 |
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| Sequence: | MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVL
NAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRV
LVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKE
GKLKP
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|
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| BDBM88769 |
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| n/a |
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| Name | BDBM88769 |
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| Synonyms: | 4-[2-(dimethylamino)ethyl-[(4-phenoxyanilino)-sulfanylidenemethyl]amino]-1-piperidinecarboxylic acid ethyl ester | 4-[2-(dimethylamino)ethyl-[(4-phenoxyphenyl)thiocarbamoyl]amino]piperidine-1-carboxylic acid ethyl ester | MLS000689506 | SMR000311544 | cid_16195551 | ethyl 4-([2-(dimethylamino)ethyl]{[(4-phenoxyphenyl)amino]carbonothioyl}amino)piperidine-1-carboxylate | ethyl 4-[2-(dimethylamino)ethyl-[(4-phenoxyphenyl)carbamothioyl]amino]piperidine-1-carboxylate |
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| Type | Small organic molecule |
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| Emp. Form. | C25H34N4O3S |
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| Mol. Mass. | 470.627 |
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| SMILES | CCOC(=O)N1CCC(CC1)N(CCN(C)C)C(=S)Nc1ccc(Oc2ccccc2)cc1 |
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| Structure | 
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