| Reaction Details |
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 | Report a problem with these data |
| Target | Dual specificity protein phosphatase 3 |
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| Ligand | BDBM88787 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay |
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| IC50 | 1930±n/a nM |
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| Citation |  PubChem, PC Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Dual specificity protein phosphatase 3 |
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| Name: | Dual specificity protein phosphatase 3 |
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| Synonyms: | DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR |
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| Type: | Hydrolase |
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| Mol. Mass.: | 20480.58 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 185 |
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| Sequence: | MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVL
NAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRV
LVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKE
GKLKP
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|
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| BDBM88787 |
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| n/a |
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| Name | BDBM88787 |
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| Synonyms: | (2Z)-2-(salicyloylhydrazono)chromene-3-carboxamide | (2Z)-2-[(2-hydroxybenzoyl)hydrazinylidene]chromene-3-carboxamide | (2Z)-2-[(2-hydroxybenzoyl)hydrazono]-2H-chromene-3-carboxamide | (2Z)-2-[(2-hydroxyphenyl)carbonylhydrazinylidene]chromene-3-carboxamide | (2Z)-2-[[(2-hydroxyphenyl)-oxomethyl]hydrazinylidene]-1-benzopyran-3-carboxamide | MLS001194671 | SMR000554966 | cid_9629545 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H13N3O4 |
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| Mol. Mass. | 323.3028 |
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| SMILES | NC(=O)c1cc2ccccc2o\c1=N/NC(=O)c1ccccc1O |
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| Structure | 
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