Ki Summary

Reaction Details

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Target

Dual specificity protein phosphatase 3

Ligand

BDBM88794

Substrate/Competitor

n/a

Meas. Tech.

Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay

IC50

21700±n/a nM

Citation

PubChem, PC Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay PubChem Bioassay(2012)[AID]

More Info.:

Get all data from this article, Assay Method

Dual specificity protein phosphatase 3

Name:

Dual specificity protein phosphatase 3

Synonyms:

Type:

Hydrolase

Mol. Mass.:

20480.58

Organism:

Homo sapiens (Human)

Description:

n/a

Residue:

185

Sequence:

MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVL
NAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRV
LVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKE
GKLKP

BDBM88794

n/a

Name

BDBM88794

Synonyms:

MLS001222829 | N-(4-Nitro-phenyl)-2-{4-[(pyridine-4-carbonyl)-hydrazonomethyl]-phenoxy}-acetamide | N-[(E)-[4-[2-(4-nitroanilino)-2-oxoethoxy]phenyl]methylideneamino]-4-pyridinecarboxamide | N-[(E)-[4-[2-(4-nitroanilino)-2-oxoethoxy]phenyl]methylideneamino]pyridine-4-carboxamide | N-[(E)-[4-[2-[(4-nitrophenyl)amino]-2-oxidanylidene-ethoxy]phenyl]methylideneamino]pyridine-4-carboxamide | N-[(E)-[4-[2-keto-2-(4-nitroanilino)ethoxy]benzylidene]amino]isonicotinamide | SMR000608052 | cid_9593322

Type

Small organic molecule

Emp. Form.

C21H17N5O5

Mol. Mass.

419.3902

SMILES

[O-][N+](=O)c1ccc(NC(=O)COc2ccc([CH+][N-]NC(=O)c3ccncc3)cc2)cc1

Structure