Ki Summary

Reaction Details

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Target

High affinity choline transporter 1

Ligand

BDBM89151

Substrate/Competitor

n/a

Meas. Tech.

Dose responses of compounds that activate the Choline Transporter (CHT) - 10 point CRC

EC50

18320±n/a nM

Citation

PubChem, PC Dose responses of compounds that activate the Choline Transporter (CHT) - 10 point CRC PubChem Bioassay(2012)[AID]

More Info.:

Get all data from this article, Assay Method

High affinity choline transporter 1

Name:

High affinity choline transporter 1

Synonyms:

CHT1 | High-affinity choline transporter | SC5A7_HUMAN | SLC5A7 | high affinity choline transporter 1

Type:

PROTEIN

Mol. Mass.:

63194.33

Organism:

Homo sapiens (Human)

Description:

ChEMBL_1464247

Residue:

580

Sequence:

MAFHVEGLIAIIVFYLLILLVGIWAAWRTKNSGSAEERSEAIIVGGRDIGLLVGGFTMTA
TWVGGGYINGTAEAVYVPGYGLAWAQAPIGYSLSLILGGLFFAKPMRSKGYVTMLDPFQQ
IYGKRMGGLLFIPALMGEMFWAAAIFSALGATISVIIDVDMHISVIISALIATLYTLVGG
LYSVAYTDVVQLFCIFVGLWISVPFALSHPAVADIGFTAVHAKYQKPWLGTVDSSEVYSW
LDSFLLLMLGGIPWQAYFQRVLSSSSATYAQVLSFLAAFGCLVMAIPAILIGAIGASTDW
NQTAYGLPDPKTTEEADMILPIVLQYLCPVYISFFGLGAVSAAVMSSADSSILSASSMFA
RNIYQLSFRQNASDKEIVWVMRITVFVFGASATAMALLTKTVYGLWYLSSDLVYIVIFPQ
LLCVLFVKGTNTYGAVAGYVSGLFLRITGGEPYLYLQPLIFYPGYYPDDNGIYNQKFPFK
TLAMVTSFLTNICISYLAKYLFESGTLPPKLDVFDAVVARHSEENMDKTILVKNENIKLD
ELALVKPRQSMTLSSTFTNKEAFLDVDSSPEGSGTEDNLQ

BDBM89151

n/a

Name

BDBM89151

Synonyms:

2-[2-(2-chlorophenyl)-1-benzimidazolyl]-N-(2-propan-2-ylphenyl)acetamide | 2-[2-(2-chlorophenyl)benzimidazol-1-yl]-N-(2-propan-2-ylphenyl)acetamide | 2-[2-(2-chlorophenyl)benzimidazol-1-yl]-N-(2-propan-2-ylphenyl)ethanamide | 2-[2-(2-chlorophenyl)benzimidazol-1-yl]-N-o-cumenyl-acetamide | MLS000389022 | SMR000255196 | cid_3418657

Type

Small organic molecule

Emp. Form.

C24H22ClN3O

Mol. Mass.

403.904

SMILES

CC(C)c1ccccc1NC(=O)Cn1c(nc2ccccc12)-c1ccccc1Cl

Structure