| Reaction Details |
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 | Report a problem with these data |
| Target | High affinity choline transporter 1 |
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| Ligand | BDBM89153 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose responses of compounds that activate the Choline Transporter (CHT) - 10 point CRC |
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| EC50 | 12260±n/a nM |
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| Citation |  PubChem, PC Dose responses of compounds that activate the Choline Transporter (CHT) - 10 point CRC PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| High affinity choline transporter 1 |
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| Name: | High affinity choline transporter 1 |
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| Synonyms: | CHT1 | High-affinity choline transporter | SC5A7_HUMAN | SLC5A7 | high affinity choline transporter 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 63194.33 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1464247 |
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| Residue: | 580 |
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| Sequence: | MAFHVEGLIAIIVFYLLILLVGIWAAWRTKNSGSAEERSEAIIVGGRDIGLLVGGFTMTA
TWVGGGYINGTAEAVYVPGYGLAWAQAPIGYSLSLILGGLFFAKPMRSKGYVTMLDPFQQ
IYGKRMGGLLFIPALMGEMFWAAAIFSALGATISVIIDVDMHISVIISALIATLYTLVGG
LYSVAYTDVVQLFCIFVGLWISVPFALSHPAVADIGFTAVHAKYQKPWLGTVDSSEVYSW
LDSFLLLMLGGIPWQAYFQRVLSSSSATYAQVLSFLAAFGCLVMAIPAILIGAIGASTDW
NQTAYGLPDPKTTEEADMILPIVLQYLCPVYISFFGLGAVSAAVMSSADSSILSASSMFA
RNIYQLSFRQNASDKEIVWVMRITVFVFGASATAMALLTKTVYGLWYLSSDLVYIVIFPQ
LLCVLFVKGTNTYGAVAGYVSGLFLRITGGEPYLYLQPLIFYPGYYPDDNGIYNQKFPFK
TLAMVTSFLTNICISYLAKYLFESGTLPPKLDVFDAVVARHSEENMDKTILVKNENIKLD
ELALVKPRQSMTLSSTFTNKEAFLDVDSSPEGSGTEDNLQ
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| BDBM89153 |
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| n/a |
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| Name | BDBM89153 |
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| Synonyms: | 4-[(E,4R)-1-(benzyloxycarbonylamino)-5-keto-2,4-dimethyl-5-(veratrylamino)pent-2-enyl]benzoic acid methyl ester | 4-[(E,4R)-5-[(3,4-dimethoxyphenyl)methylamino]-2,4-dimethyl-5-oxo-1-(phenylmethoxycarbonylamino)pent-2-enyl]benzoic acid methyl ester | MLS000563590 | SMR000389082 | cid_5459527 | methyl 4-[(E,4R)-5-[(3,4-dimethoxyphenyl)methylamino]-2,4-dimethyl-5-oxidanylidene-1-(phenylmethoxycarbonylamino)pent-2-enyl]benzoate | methyl 4-[(E,4R)-5-[(3,4-dimethoxyphenyl)methylamino]-2,4-dimethyl-5-oxo-1-(phenylmethoxycarbonylamino)pent-2-enyl]benzoate |
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| Type | Small organic molecule |
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| Emp. Form. | C32H36N2O7 |
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| Mol. Mass. | 560.6374 |
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| SMILES | COC(=O)c1ccc(cc1)C(NC(=O)OCc1ccccc1)C(\C)=C\[C@@H](C)C(=O)NCc1ccc(OC)c(OC)c1 |
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| Structure | 
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