| Reaction Details |
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 | Report a problem with these data |
| Target | High affinity choline transporter 1 |
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| Ligand | BDBM89157 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose responses of compounds that activate the Choline Transporter (CHT) - 10 point CRC |
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| EC50 | 6690±n/a nM |
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| Citation |  PubChem, PC Dose responses of compounds that activate the Choline Transporter (CHT) - 10 point CRC PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| High affinity choline transporter 1 |
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| Name: | High affinity choline transporter 1 |
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| Synonyms: | CHT1 | High-affinity choline transporter | SC5A7_HUMAN | SLC5A7 | high affinity choline transporter 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 63194.33 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1464247 |
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| Residue: | 580 |
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| Sequence: | MAFHVEGLIAIIVFYLLILLVGIWAAWRTKNSGSAEERSEAIIVGGRDIGLLVGGFTMTA
TWVGGGYINGTAEAVYVPGYGLAWAQAPIGYSLSLILGGLFFAKPMRSKGYVTMLDPFQQ
IYGKRMGGLLFIPALMGEMFWAAAIFSALGATISVIIDVDMHISVIISALIATLYTLVGG
LYSVAYTDVVQLFCIFVGLWISVPFALSHPAVADIGFTAVHAKYQKPWLGTVDSSEVYSW
LDSFLLLMLGGIPWQAYFQRVLSSSSATYAQVLSFLAAFGCLVMAIPAILIGAIGASTDW
NQTAYGLPDPKTTEEADMILPIVLQYLCPVYISFFGLGAVSAAVMSSADSSILSASSMFA
RNIYQLSFRQNASDKEIVWVMRITVFVFGASATAMALLTKTVYGLWYLSSDLVYIVIFPQ
LLCVLFVKGTNTYGAVAGYVSGLFLRITGGEPYLYLQPLIFYPGYYPDDNGIYNQKFPFK
TLAMVTSFLTNICISYLAKYLFESGTLPPKLDVFDAVVARHSEENMDKTILVKNENIKLD
ELALVKPRQSMTLSSTFTNKEAFLDVDSSPEGSGTEDNLQ
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| BDBM89157 |
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| n/a |
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| Name | BDBM89157 |
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| Synonyms: | MLS000731795 | SMR000317543 | [1-[(1-pyrimidin-2-ylpyrrol-2-yl)methyl]piperidin-3-yl]-[3-(trifluoromethyl)phenyl]methanone | [1-[[1-(2-pyrimidinyl)-2-pyrrolyl]methyl]-3-piperidinyl]-[3-(trifluoromethyl)phenyl]methanone | [1-[[1-(2-pyrimidyl)pyrrol-2-yl]methyl]-3-piperidyl]-[3-(trifluoromethyl)phenyl]methanone | cid_16191349 | {1-[(1-pyrimidin-2-yl-1H-pyrrol-2-yl)methyl]piperidin-3-yl}[3-(trifluoromethyl)phenyl]methanone |
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| Type | Small organic molecule |
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| Emp. Form. | C22H21F3N4O |
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| Mol. Mass. | 414.4235 |
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| SMILES | FC(F)(F)c1cccc(c1)C(=O)C1CCCN(Cc2cccn2-c2ncccn2)C1 |
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| Structure | 
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