Ki Summary

Reaction Details

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Target

High affinity choline transporter 1

Ligand

BDBM89166

Substrate/Competitor

n/a

Meas. Tech.

Dose responses of compounds that activate the Choline Transporter (CHT) - 10 point CRC

EC50

22440±n/a nM

Citation

PubChem, PC Dose responses of compounds that activate the Choline Transporter (CHT) - 10 point CRC PubChem Bioassay(2012)[AID]

More Info.:

Get all data from this article, Assay Method

High affinity choline transporter 1

Name:

High affinity choline transporter 1

Synonyms:

CHT1 | High-affinity choline transporter | SC5A7_HUMAN | SLC5A7 | high affinity choline transporter 1

Type:

PROTEIN

Mol. Mass.:

63194.33

Organism:

Homo sapiens (Human)

Description:

ChEMBL_1464247

Residue:

580

Sequence:

MAFHVEGLIAIIVFYLLILLVGIWAAWRTKNSGSAEERSEAIIVGGRDIGLLVGGFTMTA
TWVGGGYINGTAEAVYVPGYGLAWAQAPIGYSLSLILGGLFFAKPMRSKGYVTMLDPFQQ
IYGKRMGGLLFIPALMGEMFWAAAIFSALGATISVIIDVDMHISVIISALIATLYTLVGG
LYSVAYTDVVQLFCIFVGLWISVPFALSHPAVADIGFTAVHAKYQKPWLGTVDSSEVYSW
LDSFLLLMLGGIPWQAYFQRVLSSSSATYAQVLSFLAAFGCLVMAIPAILIGAIGASTDW
NQTAYGLPDPKTTEEADMILPIVLQYLCPVYISFFGLGAVSAAVMSSADSSILSASSMFA
RNIYQLSFRQNASDKEIVWVMRITVFVFGASATAMALLTKTVYGLWYLSSDLVYIVIFPQ
LLCVLFVKGTNTYGAVAGYVSGLFLRITGGEPYLYLQPLIFYPGYYPDDNGIYNQKFPFK
TLAMVTSFLTNICISYLAKYLFESGTLPPKLDVFDAVVARHSEENMDKTILVKNENIKLD
ELALVKPRQSMTLSSTFTNKEAFLDVDSSPEGSGTEDNLQ

BDBM89166

n/a

Name

BDBM89166

Synonyms:

2-[2-(2-Methoxy-phenyl)-acetylamino]-4-methyl-thiazole-5-carboxylic acid ethyl ester | 2-[[2-(2-methoxyphenyl)-1-oxoethyl]amino]-4-methyl-5-thiazolecarboxylic acid ethyl ester | 2-[[2-(2-methoxyphenyl)acetyl]amino]-4-methyl-thiazole-5-carboxylic acid ethyl ester | MLS001208615 | SMR000524782 | cid_6490609 | ethyl 2-[2-(2-methoxyphenyl)ethanoylamino]-4-methyl-1,3-thiazole-5-carboxylate | ethyl 2-[[2-(2-methoxyphenyl)acetyl]amino]-4-methyl-1,3-thiazole-5-carboxylate

Type

Small organic molecule

Emp. Form.

C16H18N2O4S

Mol. Mass.

334.39

SMILES

CCOC(=O)c1sc(NC(=O)Cc2ccccc2OC)nc1C

Structure