| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Zinc finger protein GLI1 |
|---|
| Ligand | BDBM89339 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Dose response confirmation of uHTS antagonist hits from Gli-SUFU in a luminescent reporter assay |
|---|
| IC50 | 294±n/a nM |
|---|
| Citation |  PubChem, PC Dose response confirmation of uHTS antagonist hits from Gli-SUFU in a luminescent reporter assay PubChem Bioassay(2012)[AID] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Zinc finger protein GLI1 |
|---|
| Name: | Zinc finger protein GLI1 |
|---|
| Synonyms: | GLI1_MOUSE | Gli | Gli1 | Glioma-associated oncogene homolog |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 118579.34 |
|---|
| Organism: | Mus musculus |
|---|
| Description: | EBI_101259 |
|---|
| Residue: | 1111 |
|---|
| Sequence: | MFNPMTPPQVNSYSEPCCLRPLHSQGVPSMGTEGLSGLPFCHQANFMSGSQGYGAARETS
SCTEGSLFPPPPPPRSSVKLTKKRALSISPLSDASLDLQTVIRTSPSSLVAFINSRCTSP
GGSYGHLSIGTMSPSLGFPPQMSHQKGTSPPYGVQPCVPHDSTRGSMMLHPQSRGPRATC
QLKSELDMMVGKCPEDPLEGDMSSPNSTGTQDHLLGMLDGREDLEREEKPEPESVYETDC
RWDGCSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTG
EKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEQEGCSKAFSNASDRAKHQNRTHS
NEKPYVCKLPGCTKRYTDPSSLRKHVKTVHGPDAHVTKRHRGDGPLPRAQPLSTVEPKRE
REGGSGREESRLTVPESAMPQQSPGAQSSCSSDHSPAGSAANTDSGVEMAGNAGGSTEDL
SSLDEGPCVSATGLSTLRRLENLRLDQLHQLRPIGSRGLKLPSLTHAGAPVSRRLGPPVS
LDRRSSSSSSMSSAYTVSRRSSLASPFPPGTPPENGASSLPGLTPAQHYMLRARYASARG
SGTPPTAAHSLDRMGGLSVPPWRSRTEYPGYNPNAGVTRRASDPARAADHPAPARVQRFK
SLGCVHTPPSVATGRNFDPHHPTSVYSPQPPSITENVAMDTRGLQEEPEVGTSVMGNGLN
PYMDFSSTDTLGYGGPEGTAAEPYEARGPGSLPLGPGPPTNYGPGHCAQQVSYPDPTPEN
WGEFPSHAGVYPSNKAPGAAYSQCPRLEHYGQVQVKPEQGCPVGSDSTGLAPCLNAHPSE
GSPGPQPLFSHHPQLPQPQYPQSGPYPQPPHGYLSTEPRLGLNFNPSSSHSTGQLKAQLV
CNYVQSQQELLWEGRNRGGLPNQELPYQSPKFLGGSQVSQSPAKTPAAAAAAYGSGFAPA
SANHKSGSYPAPSPCHETFTVGVNRPSHRPAAPPRLLPPLSPCYGPLKVGDTNPSCGHPE
VGRLGAGPALYPPPEGQVCNALDSLDLDNTQLDFVAILDEAQGLSPPLSHEQGDSSKNTP
SPSGPPNMAVGNMSVLLGSLPGETQFLNSSA
|
|
|
|---|
| BDBM89339 |
|---|
| n/a |
|---|
| Name | BDBM89339 |
|---|
| Synonyms: | MLS001018415 | N-(6-piperidin-1-ylpyrimidin-4-yl)benzamide | N-(6-piperidinopyrimidin-4-yl)benzamide | N-[6-(1-piperidinyl)-4-pyrimidinyl]benzamide | SMR000354663 | cid_1540596 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H18N4O |
|---|
| Mol. Mass. | 282.3403 |
|---|
| SMILES | O=C(Nc1cc(ncn1)N1CCCCC1)c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
