| Reaction Details |
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 | Report a problem with these data |
| Target | Zinc finger protein GLI1 |
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| Ligand | BDBM75549 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response confirmation of uHTS antagonist hits from Gli-SUFU in a luminescent reporter assay |
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| IC50 | 2790±n/a nM |
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| Citation |  PubChem, PC Dose response confirmation of uHTS antagonist hits from Gli-SUFU in a luminescent reporter assay PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Zinc finger protein GLI1 |
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| Name: | Zinc finger protein GLI1 |
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| Synonyms: | GLI1_MOUSE | Gli | Gli1 | Glioma-associated oncogene homolog |
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| Type: | PROTEIN |
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| Mol. Mass.: | 118579.34 |
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| Organism: | Mus musculus |
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| Description: | EBI_101259 |
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| Residue: | 1111 |
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| Sequence: | MFNPMTPPQVNSYSEPCCLRPLHSQGVPSMGTEGLSGLPFCHQANFMSGSQGYGAARETS
SCTEGSLFPPPPPPRSSVKLTKKRALSISPLSDASLDLQTVIRTSPSSLVAFINSRCTSP
GGSYGHLSIGTMSPSLGFPPQMSHQKGTSPPYGVQPCVPHDSTRGSMMLHPQSRGPRATC
QLKSELDMMVGKCPEDPLEGDMSSPNSTGTQDHLLGMLDGREDLEREEKPEPESVYETDC
RWDGCSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTG
EKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEQEGCSKAFSNASDRAKHQNRTHS
NEKPYVCKLPGCTKRYTDPSSLRKHVKTVHGPDAHVTKRHRGDGPLPRAQPLSTVEPKRE
REGGSGREESRLTVPESAMPQQSPGAQSSCSSDHSPAGSAANTDSGVEMAGNAGGSTEDL
SSLDEGPCVSATGLSTLRRLENLRLDQLHQLRPIGSRGLKLPSLTHAGAPVSRRLGPPVS
LDRRSSSSSSMSSAYTVSRRSSLASPFPPGTPPENGASSLPGLTPAQHYMLRARYASARG
SGTPPTAAHSLDRMGGLSVPPWRSRTEYPGYNPNAGVTRRASDPARAADHPAPARVQRFK
SLGCVHTPPSVATGRNFDPHHPTSVYSPQPPSITENVAMDTRGLQEEPEVGTSVMGNGLN
PYMDFSSTDTLGYGGPEGTAAEPYEARGPGSLPLGPGPPTNYGPGHCAQQVSYPDPTPEN
WGEFPSHAGVYPSNKAPGAAYSQCPRLEHYGQVQVKPEQGCPVGSDSTGLAPCLNAHPSE
GSPGPQPLFSHHPQLPQPQYPQSGPYPQPPHGYLSTEPRLGLNFNPSSSHSTGQLKAQLV
CNYVQSQQELLWEGRNRGGLPNQELPYQSPKFLGGSQVSQSPAKTPAAAAAAYGSGFAPA
SANHKSGSYPAPSPCHETFTVGVNRPSHRPAAPPRLLPPLSPCYGPLKVGDTNPSCGHPE
VGRLGAGPALYPPPEGQVCNALDSLDLDNTQLDFVAILDEAQGLSPPLSHEQGDSSKNTP
SPSGPPNMAVGNMSVLLGSLPGETQFLNSSA
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| BDBM75549 |
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| n/a |
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| Name | BDBM75549 |
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| Synonyms: | (4-Methoxy-benzyl)-(5H-pyrimido[5,4-b]indol-4-yl)-amine | MLS000768346 | N-[(4-methoxyphenyl)methyl]-5H-pyrimido[5,4-b]indol-4-amine | SMR000431667 | cid_921775 | p-anisyl(5H-pyrimid[5,4-b]indol-4-yl)amine |
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| Type | Small organic molecule |
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| Emp. Form. | C18H16N4O |
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| Mol. Mass. | 304.3458 |
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| SMILES | COc1ccc(CNc2ncnc3c4ccccc4[nH]c23)cc1 |
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| Structure | 
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